FITC标记的桥粒芯蛋白3抗体
产品名称： FITC标记的桥粒芯蛋白3抗体
英文名称： Anti-Desmoglein 3/FITC
产品编号： HZ-6585R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-Desmoglein 3/FITC Conjugated antibody
FITC标记的桥粒芯蛋白3抗体
| 英文名称 | Anti-Desmoglein 3/FITC |
| 中文名称 | FITC标记的桥粒芯蛋白3抗体 |
| 别 名 | 130 kD pemphigus vulgaris antigen; Balding; CDHF 6; CDHF6; Desmoglein 3 precursor; Desmoglein3; DKFZp686P23184; DSG 3; DSG3; DSG-3; Pemphigus vulgaris antigen; PVA; DSG3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 细胞粘附分子 细胞骨架 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 105kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Desmoglein 3 (50-75aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. Tissue Specificity: Epidermis, tongue, tonsil, esophagus and carcinomas. Similarity: Contains 4 cadherin domains. Database links: UniProtKB/Swiss-Prot: P32926.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
桥粒是上皮、心肌和某些其他细胞类型之间的细胞-细胞连接。桥粒芯糖蛋白3是脊椎动物上皮细胞桥粒的钙结合跨膜糖蛋白组分。目前已鉴定出三种桥粒芯蛋白亚家族成员，均为钙粘蛋白细胞粘附分子超家族成员。这些桥粒芯蛋白基因家族成员位于18号染色体上的一个簇中。该蛋白已被鉴定为自身免疫性皮肤疱疱疮性寻常型天疱疮的自身抗原。