FITC标记的SAMD14抗体
产品名称: FITC标记的SAMD14抗体
英文名称: Anti-SAMD14/FITC
产品编号: HZ-6578R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SAMD14/FITC Conjugated antibody
FITC标记的SAMD14抗体
英文名称 | Anti-SAMD14/FITC |
中文名称 | FITC标记的SAMD14抗体 |
别 名 | SAMD14; SAMD-14; sterile alpha motif domain containing 14; SAM14_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 肿瘤细胞生物标志物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SAMD14 (241-285aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The sterile alpha motif (SAM) domain is a 70 residue structure found in a large number of proteins involved in diverse processes present throughout eukaryotes. The SAM domain is known to bind RNA and is arranged in a small five-helix bundle with two large interfaces. SAMD14 (sterile alpha motif domain-containing protein 14) is a 417 amino acid protein encoded by the SAMD14 gene which maps to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease. Similarity: Contains 1 SAM (sterile alpha motif) domain. Database links: UniProtKB/Swiss-Prot: Q8IZD0.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
无菌α基序(山姆)结构域是一个70残基结构,在大量的蛋白质中发现,涉及到在真核生物中存在的各种过程。山姆域已知结合RNA,并被布置在具有两个大界面的小五螺旋束中。SAMD14(无菌α基序结构域蛋白14)是由SAMD14基因编码的417氨基酸蛋白,其编码到人类染色体17。第17号染色体占人类基因组的2.5%以上,约有8100万个碱基编码超过1200个基因。两个关键的肿瘤抑制基因与17号染色体相关,即p53和BRCA1。第17号染色体也与神经纤维瘤病有关,其特征是神经和表皮损伤,Schwann细胞生长失调,亚力山大病,Bito-Hog Dube综合征和Cavava病。