FITC标记的前列腺相关P抗原家族成员1抗体
产品名称: FITC标记的前列腺相关P抗原家族成员1抗体
英文名称: Anti-PAGE1/FITC
产品编号: HZ-6561R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-PAGE1/FITC Conjugated antibody
FITC标记的前列腺相关P抗原家族成员1抗体
英文名称 | Anti-PAGE1/FITC |
中文名称 | FITC标记的前列腺相关P抗原家族成员1抗体 |
别 名 | AL5; G antigen family B member 1; GAGE 9; GAGE9; GAGEB1; P antigen family, member 1 (prostate associated); PAGE 1; GAGB1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 肿瘤细胞生物标志物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 16kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PAGE1 (51-95aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. Tissue Specificity: Isolated from prostate cancer cell lines; expression associated with progression to androgen insensitive phenotype. Expressed in normal testis and at lower level in normal placenta. Similarity: Belongs to the GAGE family. Database links: Entrez Gene: 8712 Human Omim: 300288 Human SwissProt: O75459 Human Unigene: 128231 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因属于一个家族的基因,在各种肿瘤中表达,但不在正常组织中,除了睾丸。家族成员的序列高度相关,但不同的是分散的核苷酸替换。抗原肽YrPRPRRY,也由其他几个家族成员编码,是由自体溶细胞T淋巴细胞识别的。目前尚不清楚这种蛋白质的功能。选择性剪接导致多个转录变体。