FITC标记的富含亮氨酸重复神经元5抗体
产品名称： FITC标记的富含亮氨酸重复神经元5抗体
英文名称： Anti-LRRN5/FITC
产品编号： HZ-6545R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 所在区域 : 上海
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Rabbit Anti-LRRN5/FITC Conjugated antibody
FITC标记的富含亮氨酸重复神经元5抗体
| 英文名称 | Anti-LRRN5/FITC |
| 中文名称 | FITC标记的富含亮氨酸重复神经元5抗体 |
| 别 名 | Fibronectin type III immunoglobulin and leucine rich repeat domain 7; FIGLER7; GAC 1; GAC1; Glioma amplified on chromosome 1; Glioma amplified on chromosome 1 protein; Leucine rich and ankyrin repeats 1; Leucine rich repeat neuronal 2; Leucine rich repeat neuronal 5; Leucine rich repeat neuronal protein 2; Leucine rich repeat neuronal protein 5; LRANK 1; LRANK1; LRRN 2; LRRN 5; LRRN2; LRRN2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 77kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LRRN5 (591-637aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: Overamplified in malignant gliomas. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 12 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: UniProtKB/Swiss-Prot: O75325.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白属于富含亮氨酸的重复超家族。该基因被发现在恶性胶质瘤中被扩增和过表达。编码蛋白与作为细胞粘附分子或信号转导受体的其他蛋白具有同源性，是恶性胶质瘤中1q32.1扩增子的靶基因候选物。两个交替编码的转录本变体编码相同的蛋白质已被描述为这个基因。