FITC标记的翻译控制肿瘤蛋白抗体
产品名称： FITC标记的翻译控制肿瘤蛋白抗体
英文名称： Anti-TCTP/FITC
产品编号： HZ-3578R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-TCTP/FITC Conjugated antibody
FITC标记的翻译控制肿瘤蛋白抗体
| 英文名称 | Anti-TCTP/FITC |
| 中文名称 | FITC标记的翻译控制肿瘤蛋白抗体 |
| 别 名 | TPT1-like protein; TPT1L + TCTP; TPT1L_HUMAN; FLJ27337; Fortilin; Histamine releasing factor; Histamine-releasing factor; HRF; Immunoglobulin E-dependent; p02; p23; TCTP; TCTP_HUMAN; TPT1; Translationally controlled tumor protein; Translationally-controlled tumor protein; Tumor protein translationally controlled 1; tumor protein translationally-controlled 1; tumor protein, translationally-controlled 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TCTP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM). Function: Involved in calcium binding and microtubule stabilization. Subunit: Interacts with STEAP3. Subcellular Location: Cytoplasm. Tissue Specificity: Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate. Similarity: Belongs to the TCTP family. Database links: Entrez Gene: 7178 Human Entrez Gene: 22070 Mouse Entrez Gene: 116646 Rat Omim: 600763 Human SwissProt: P13693 Human SwissProt: P63028 Mouse SwissProt: P63029 Rat Unigene: 374596 Human Unigene: 296922 Mouse Unigene: 297482 Mouse Unigene: 36610 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 翻译控制肿瘤蛋白最初发现于肿瘤组织，后来又从其他组织中相继分离出来,是许多动物肿瘤细胞中存在的一类较丰富的蛋白,TCTP参与钙离子结合和微管的稳定,是一类广泛存在于动物、植物及酵母中的、在序列上高度保守且具有很高表达量的蛋白家族 |
TCTP参与钙结合和微管稳定。它是由过敏性儿童淋巴细胞产生的免疫球蛋白E依赖性组胺释放因子，并存在于变态反应患者的生物液体中。人类和小鼠重组HRF蛋白导致来自人嗜碱性粒细胞的组胺释放的供体亚群（从OMIM引用）。