FITC标记的磷酸化谷氨酸受体2A抗体-抗体-抗体-生物在线
FITC标记的磷酸化谷氨酸受体2A抗体

FITC标记的磷酸化谷氨酸受体2A抗体

商家询价

产品名称: FITC标记的磷酸化谷氨酸受体2A抗体

英文名称: Anti-Phospho-NMDAR2A (Tyr1325)/FITC

产品编号: HZ-3305R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-Phospho-NMDAR2A (Tyr1325)/FITC Conjugated antibody

FITC标记的磷酸化谷氨酸受体2A抗体

 

英文名称 Anti-Phospho-NMDAR2A (Tyr1325)/FITC
中文名称 FITC标记的磷酸化谷氨酸受体2A抗体
别    名 NMDAR2A (phospho Y1325); p-NMDAR2A (phospho Y1325); Glutamate [NMDA] receptor subunit epsilon 1; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate receptor; Glutamate receptor ionotropic N methyl D aspartate 2A; GRIN 2A; GRIN2A; HNR2A; N methyl D aspartate receptor channel, subunit epsilon 1; N Methyl D Aspartate Receptor Subtype 2A; N methyl D aspartate receptor subunit 2A; N-methyl D-aspartate receptor subtype 2A; NMDA receptor subtype 2A; NMDA Receptor Type 2A; NMDAR 2A; NMDAR2A; NMDE1_HUMAN; NR 2A; NR2A; OTTHUMP00000160135; OTTHUMP00000174531.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 细胞生物  免疫学  神经生物学  细胞膜受体  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 163kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Tyr1325
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Function:
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits (By similarity).

Subunit:
Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Found in a complex with GRIN1 and GRIN3B. Found in a complex with GRIN1, GRIN3A and PPP2CB. Interacts with PDZ domains of AIP1, INADL and DLG4. Interacts with HIP1 and NETO1 (By similarity). Interacts with LRFN2 (By similarity). 

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2A/GRIN2A subfamily.

Database links:

Entrez Gene: 2903 Human

Entrez Gene: 14811 Mouse

Entrez Gene: 24409 Rat

Omim: 138253 Human

SwissProt: Q12879 Human

SwissProt: P35436 Mouse

SwissProt: Q00959 Rat

Unigene: 411472 Human

Unigene: 2953 Mouse

Unigene: 9710 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

N-甲基-D-天门冬氨酸(NMDA)受体是一类离子型谷氨酸门控离子通道。这些受体已被证明参与长时程增强,突触传递的效率依赖于某些类型的记忆和学习的活动依赖性增加。NMDA受体通道是由关键受体亚基NMDAR1(GRIN1)和4个nMdAR2亚基中的1个或多个组成的异构体:NMDA 2A(GRAN2A)、NMDA 2B(GRAN2B)、NMDA 2C(GRAN2C)和NMDA 2D(GRAN2D)。另一种编码不同的异构体的剪接转录变体已被发现用于该基因。[ RefSeq,Aug 2008提供]