FITC标记的肌酸磷酸激酶2抗体
产品名称： FITC标记的肌酸磷酸激酶2抗体
英文名称： Anti-CKMT2/FITC
产品编号： HZ-3526R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-CKMT2/FITC Conjugated antibody
FITC标记的肌酸磷酸激酶2抗体
| 英文名称 | Anti-CKMT2/FITC |
| 中文名称 | FITC标记的肌酸磷酸激酶2抗体 |
| 别 名 | CKMT 2; Basic-type mitochondrial creatine kinase; CKMT 2; CKMT2; CPK; Creatine kinase mitochondrial 2; Creatine kinase mitochondrial 2 (sarcomeric); Creatine kinase S-type; creatine kinase S-type, mitochondrial; Creatine kinase, sarcomeric mitochondrial; KCRS_HUMAN; Mib CK; Mib-CK; mitochondrial; OTTHUMP00000147542; S-MtCK; Sarcomeric mitochondrial creatine kinase; SMTCK. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 免疫学 转录调节因子 激酶和磷酸酶 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 46kDa |
| 细胞定位 | 细胞膜 线粒体 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CKMT2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: CKMT2 (creatine kinase, mitochondrial 2 (sarcomeric)) is a creatine kinase isoenzyme, (reversibly) catalyzing the production of ATP from ADP by converting Phosphocreatine to creatine. Phosphocreatine serves as an energy reservoir for the rapid generation of ATP.Mitochondrial creatine kinase exists as two isoenzymes, sarcomeric mitochondrial creatine kinase (CKMT2) and ubiquitous creatine kinase; these are encoded by separate genes. Mitochondrial creatine kinases occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. The CKMT2 gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Subunit: Exists as an octamer composed of four CKMT2 homodimers. Subcellular Location: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Tissue Specificity: Sarcomere-specific. Found only in heart and skeletal muscles. Similarity: Belongs to the ATP:guanido phosphotransferase family. Contains 1 phosphagen kinase C-terminal domain. Contains 1 phosphagen kinase N-terminal domain. Database links: Entrez Gene: 538944 Cow Entrez Gene: 1160 Human Entrez Gene: 76722 Mouse Entrez Gene: 688698 Rat Omim: 123295 Human SwissProt: Q3ZBP1 Cow SwissProt: P17540 Human SwissProt: Q6P8J7 Mouse SwissProt: P09605 Rat Unigene: 80691 Human Unigene: 316438 Mouse Unigene: 162549 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
（2 ckmt2线粒体肌酸激酶（横纹肌），肌酸激酶同工酶是（a），（reversibly）catalyzing生产ATP和ADP的转换到肌酸磷酸肌酸。磷酸肌酸作为能源水库提供的快速一代线粒体肌酸激酶值为ATP。肌酸激酶两isoenzymes，横纹肌线粒体肌酸激酶（ckmt2）和无处不在的；这是由单独的基因编码。线粒体肌酸激酶发生在两种不同的形式：二聚体和低聚octamers二聚体，在对比的是cytosolic isoenzymes肌酸激酶。人心肌线粒体肌酸激酶有80 %的外显子编码脢（无处不在的线粒体肌酸激酶。一个序列的同源ckmt2基因包含几个主题是共享的一些核基因编码的蛋白质在线粒体和因此可能是重要的协调激活这些基因在线粒体生物合成。三成绩单编码蛋白变异的变化已经发现这个基因。