FITC标记的肿瘤坏死因子C/淋巴毒素β抗体
产品名称: FITC标记的肿瘤坏死因子C/淋巴毒素β抗体
英文名称: Anti-Lymphotoxin Beta/FITC
产品编号: HZ-10063R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围:
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-Lymphotoxin Beta/FITC Conjugated antibody
FITC标记的肿瘤坏死因子C/淋巴毒素β抗体
英文名称 | Anti-Lymphotoxin Beta/FITC |
中文名称 | FITC标记的肿瘤坏死因子C/淋巴毒素β抗体 |
别 名 | LT beta; LT-beta; LTB; lymphotoxin beta (TNF superfamily, member 3); lymphotoxin beta; lymphotoxin-beta; OTTHUMP00000038214; p33; TNF C; TNF-C; TNFC; TNFC_HUMAN; TNFSF3; tumor necrosis factor C (lymphotoxin beta); tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 免疫学 信号转导 生长因子和激素 细胞因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, |
产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 25kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Lymphotoxin Beta |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms. Function: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. Subunit: Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Spleen and thymus. Similarity: Belongs to the tumor necrosis factor family. Database links: Entrez Gene: 4050 Human Entrez Gene: 16994 Mouse Omim: 600978 Human SwissProt: Q06643 Human SwissProt: P41155 Mouse Unigene: 376208 Human Unigene: 1715 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
淋巴毒素β是TNF家族的一种II型膜蛋白。它通过异三聚体的形成将淋巴毒素α锚定到细胞表面。在淋巴细胞表面的主要形式是淋巴毒素α1β2和/这复杂复杂的淋巴毒素-β受体的主要配体。LTB是炎症反应系统的诱导物,参与淋巴组织的正常发育。淋巴毒素β异构体B可能是非功能性的。选择性剪接导致多个转录子变体编码不同的亚型。