FITC标记的对接蛋白EFS抗体
产品名称： FITC标记的对接蛋白EFS抗体
英文名称： Anti-EFS/FITC
产品编号： HZ-13060R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-EFS/FITC Conjugated antibody
FITC标记的对接蛋白EFS抗体
| 英文名称 | Anti-EFS/FITC |
| 中文名称 | FITC标记的对接蛋白EFS抗体 |
| 别 名 | CAS3; CASS3; EFS1; EFS2; Embryonal Fyn associated substrate; HEFS; SIN; EFS_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞粘附分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 59kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EFS |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: EFS is a docking protein which plays a pivotal role for cell adhesion-related intracellular tyrosine kinase signaling, where it may serve as an activator of SRC and is known to interat with the SH3 domain of FYN and with CRK, SRC, and YES. Function: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity). Subcellular Location: Cytoplasm Tissue Specificity: The protein has been detected in lung and placenta. Post-translational modifications: Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC (By similarity). Similarity: Belongs to the CAS family. Contains 1 SH3 domain. Database links: UniProtKB/Swiss-Prot: O43281.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
EFS是一种对接蛋白，在细胞粘附相关的细胞内酪氨酸激酶信号转导中起着关键作用，它可作为SRC的激活剂，并已知与FYN的SH3结构域和CRK、SRC和YES相互作用。