FITC标记的胞吐囊复合体蛋白2抗体
产品名称: FITC标记的胞吐囊复合体蛋白2抗体
英文名称: Anti-EXOC2/FITC
产品编号: HZ-13118R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 邮编 : 200612
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Rabbit Anti-EXOC2/FITC Conjugated antibody
FITC标记的胞吐囊复合体蛋白2抗体
英文名称 | Anti-EXOC2/FITC |
中文名称 | FITC标记的胞吐囊复合体蛋白2抗体 |
别 名 | exocyst complex component 2; exocyst complex component Sec5; FLJ11026; SEC5; SEC5 like 1; SEC5L1; Sec5p; EXOC2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 转录调节因子 转运蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 104kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EXOC2/SEC5 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The mammalian exocyst complex (sec 6/8) is a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Sec 5 is one of eight exocyst complex subunits: Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84. Exocyst complex regulation depends upon Sec5 binding Ral in a GTP-dependent manner. Human Sec5 maps to chromosome 6p25.3. Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Subunit: The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with EXOC3L1 (By similarity). Interacts with RALA and GNEFR/DELGEF. Interaction with GNEFR occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP. Interacts with RALB. Subcellular Location: Plasma membrane. Tissue Specificity: Widely expressed with highest levels in brain and placenta. Similarity: Belongs to the SEC5 family. Contains 1 IPT/TIG domain. Database links: Entrez Gene: 55770 Human Entrez Gene: 66482 Mouse Entrez Gene: 171455 Rat SwissProt: Q96KP1 Human SwissProt: Q9D4H1 Mouse SwissProt: O54921 Rat Unigene: 484412 Human Unigene: 293510 Mouse Unigene: 2869 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
哺乳动物外囊复合体(sec 6/8)是一种多蛋白复合体,对于将外囊泡靶向到质膜上的特定对接位点是必不可少的。SEC 5是八个胞外复合体亚基:SEC3、SEC5、SEC6、SEC8、SEC10、SEC15、EXO70和EXO84中的一个。胞囊复合物调节依赖于SEC5结合的GRAP依赖性的RAL。人类SEC5映射到染色体6P25.3。