FITC标记的胆碱磷酸转移酶1抗体
产品名称： FITC标记的胆碱磷酸转移酶1抗体
英文名称： Anti-SCP3/FITC
产品编号： HZ-10660R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SCP3/FITC Conjugated antibody
FITC标记的胆碱磷酸转移酶1抗体
| 英文名称Anti-SCP3/FITC中文名称FITC标记的胆碱磷酸转移酶1抗体别 名SCP3; choline phosphotransferase 1; chpt1; COR 1; COR1; MGC71888; RNASCP3; SCP 3; SCP-3; SPGF4; Sycp 3; Sycp3; SYCP3_HUMAN; Synaptonemal complex protein 3. 规格价格100ul/2980元 购买 大包装/询价说 明 书100ul 研究领域细胞生物 染色质和核信号 细胞周期蛋白 细胞分化 抗体来源Rabbit克隆类型Polyclonal交叉反应Human, Mouse, Rat, 产品应用ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.分 子 量27kDa性 状Lyophilized or Liquid浓 度1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human SYCP3亚 型IgG纯化方法affinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.产品介绍background: This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010] Function: Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2. Subunit: Interacts with SYCP2. Subcellular Location: Nucleus. Chromosome. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed. Tissue Specificity: Testis-specific. Post-translational modifications: Phosphorylated. DISEASE: Spermatogenic failure 4 (SPGF4) [MIM:270960]: An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the XLR/SYCP3 family. Database links: Entrez Gene: 50511 Human Entrez Gene: 20962 Mouse Entrez Gene: 25561 Rat Omim: 604759 Human SwissProt: Q8IZU3 Human SwissProt: P70281 Mouse SwissProt: Q63520 Rat Unigene: 506504 Human Unigene: 297977 Mouse Unigene: 34889 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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该基因编码突触结构复合体的基本结构成分。该复合物参与减数分裂染色体的突触、重组和分离。该基因突变与男性无精子症和女性对妊娠丢失的易感性有关。交替剪接导致编码同一蛋白质的多个转录变体。[ RefSeq，2010年5月提供]