FITC标记的甘油二酯激酶γ/DGK-γ抗体
产品名称： FITC标记的甘油二酯激酶γ/DGK-γ抗体
英文名称： Anti-DGKG/FITC
产品编号： HZ-14297R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DGKG/FITC Conjugated antibody
FITC标记的甘油二酯激酶γ/DGK-γ抗体
| 英文名称 | Anti-DGKG/FITC |
| 中文名称 | FITC标记的甘油二酯激酶γ/DGK-γ抗体 |
| 别 名 | DAG kinase gamma; DAGK3; DGK gamma; DGKG; DGKG_HUMAN； diacylglycerol kinase gamma 90kDa; Diacylglycerol kinase gamma; Diglyceride kinase; Diglyceride kinase gamma. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 89kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DGKE |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: DGKG (Diacylglycerol kinase gamma ) reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid. This enzyme initiates resynthesis of phosphoinositides consumed by phospholipase C during cellular signal transduction. DGK gamma is one of multiple DGK isozymes found in animal cells. It is expressed abundantly in the human retina and to a much lesser extent in the brain. Other tissues contain extremely low levels. Subcellular Location: Cell Membrane and Cytoplasmic. Database links: Entrez Gene: 1608 Human Entrez Gene: 110197 Mouse Entrez Gene: 25666 Rat Omim: 601854 Human SwissProt: P49619 Human SwissProt: Q2M1H4 Human SwissProt: Q5FWG1 Human SwissProt: Q91WG7 Mouse SwissProt: P49620 Rat Unigene: 683449 Human Unigene: 194986 Mouse Unigene: 10544 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
这个基因编码一种酶，它是二酰甘油激酶I型亚家族的成员，参与脂质代谢。这些酶通过催化二酰甘油的磷酸化来产生磷脂酸，二酰甘油是一种基本的脂质第二信使，可以激活许多蛋白质，包括蛋白激酶C亚型、Ras鸟嘌呤核苷酸释放蛋白和一些瞬时受体电位通道。二酰甘油激酶γ参与白血病细胞的细胞周期调节和巨噬细胞分化的负调控。该基因已发现编码不同亚型的多个转录变体。[ RefSeq，JUL 2008 ]