FITC标记的ATP-依赖的RNA解旋酶30抗体
产品名称： FITC标记的ATP-依赖的RNA解旋酶30抗体
英文名称： Anti-DHX30/FITC
产品编号： HZ-14313R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DHX30/FITC Conjugated antibody
FITC标记的ATP-依赖的RNA解旋酶30抗体
| 英文名称 | Anti-DHX30/FITC |
| 中文名称 | FITC标记的ATP-依赖的RNA解旋酶30抗体 |
| 别 名 | DDX30; DEAH box protein 30; Dhx30; DHX30_HUMAN; FLJ11214; KIAA0890; Putative ATP-dependent RNA helicase DHX30; Ret CoR. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 细胞分化 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 134kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DHX30 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013] Subcellular Location: Cytoplasm and Mitochondrion. Cytoplasm. Mitochondrion matrix > mitochondrion nucleoid. Post-translational modifications: Isoform 2 is phosphorylated on Ser-15. Similarity: Belongs to the DEAD box helicase family. DEAH subfamily. Contains 1 DRBM (double-stranded RNA-binding) domain. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Database links: Entrez Gene: 22907 Human Entrez Gene: 72831 Mouse Entrez Gene: 367172 Rat GenBank: NM_138614 Human SwissProt: Q7L2E3 Human SwissProt: Q7L2E3-2 Human SwissProt: Q99PU8 Mouse SwissProt: Q5BJS0 Rat Unigene: 517948 Human Unigene: 276305 Mouse Unigene: 163034 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
死盒蛋白，其特征在于保守的基序ASP Glu ALA-ASP（死亡），是假定的RNA解旋酶。它们涉及许多涉及RNA二级结构改变的细胞过程，如翻译起始、核和线粒体剪接、核糖体和剪接体组装。基于它们的分布模式，这种死亡盒蛋白家族的一些成员被认为参与胚胎发生、精子发生和细胞生长和分裂。由该基因编码的家族成员是与线粒体DNA相关的线粒体核蛋白。它还被鉴定为在视网膜发育中起作用的转录抑制复合物的组成部分，并且需要优化锌指抗病毒蛋白的功能。另一种剪接转录变体已经发现这个基因。[ RefSeq，FEB 2013 ]提供