FITC标记的耳聋常染色体显性遗传相关蛋白3抗体-抗体-抗体-生物在线
FITC标记的耳聋常染色体显性遗传相关蛋白3抗体

FITC标记的耳聋常染色体显性遗传相关蛋白3抗体

商家询价

产品名称: FITC标记的耳聋常染色体显性遗传相关蛋白3抗体

英文名称: Anti-DIAPH3/FITC

产品编号: HZ-14325R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : www.shzbio.net

 Rabbit Anti-DIAPH3/FITC Conjugated antibody 

FITC标记的耳聋常染色体显性遗传相关蛋白3抗体

 

英文名称 Anti-DIAPH3/FITC
中文名称 FITC标记的耳聋常染色体显性遗传相关蛋白3抗体
别    名 AN; AUNA1; Dia2; diap3; DIAP3_HUMAN; DIAPH3; Diaphanous homolog 3 (Drosophila); Diaphanous homolog 3; Diaphanous related formin 3; Diaphanous-related formin-3; DKFZp434C0931; DKFZp686A13178; DRF3; FLJ34705; mDia2; NSDAN; OTTHUMP00000018480; Protein diaphanous homolog 3; RP11-26P21.1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  细胞粘附分子  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 137kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DIAPH3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Function:
Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.

Similarity:
Belongs to the formin homology family. Diaphanous subfamily.
Contains 1 DAD (diaphanous autoregulatory) domain.
Contains 1 FH1 (formin homology 1) domain.
Contains 1 FH2 (formin homology 2) domain.
Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.

Database links:

Entrez Gene: 81624 Human

Omim: 614567 Human

SwissProt: Q9NSV4 Human

Unigene: 283127 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

这个基因编码一个成员的透明亚家族的形成素家族。该家族成员参与肌动蛋白重塑和调节细胞运动和粘附。该基因突变与常染色体显性遗传性听神经病1有关。该基因已发现编码不同亚型的多个转录变体。[由RefSeq,APR 2012提供]