FITC标记的血管内皮生长因子D型抗体
产品名称： FITC标记的血管内皮生长因子D型抗体
英文名称： Anti-VEGF-D/FITC
产品编号： HZ-10259R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-VEGF-D/FITC Conjugated antibody
FITC标记的血管内皮生长因子D型抗体
| 英文名称 | Anti-VEGF-D/FITC |
| 中文名称 | FITC标记的血管内皮生长因子D型抗体 |
| 别 名 | Vascular Endothelial Growth Factor D; VEGFD; VEGF D; FIGF; VEGFD_HUMAN; VEGF-D; c-Fos-induced growth factor. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VEGF-D |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]. Function: Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors. [SUBUNIT] Homodimer; non-covalent and antiparallel. Subunit: Homodimer; non-covalent and antiparallel. Subcellular Location: Secreted. Tissue Specificity: Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. Post-translational modifications: Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions. Similarity: Belongs to the PDGF/VEGF growth factor family. Database links: Entrez Gene: 2277 Human Entrez Gene: 14205 Mouse Entrez Gene: 360457 Rat Omim: 300091 Human SwissProt: O43915 Human SwissProt: P97946 Mouse SwissProt: O35251 Rat Unigene: 11392 Human Unigene: 297978 Mouse Unigene: 10796 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白是血小板衍生生长因子/血管内皮生长因子(PDGF/VEGF)家族的成员，在血管生成、淋巴管生成和内皮细胞生长方面具有活性。这种分泌的蛋白质经历复杂的蛋白水解成熟，产生结合和激活VEGFR-2和VEGFR-3受体的多种加工形式。该蛋白质在结构和功能上类似于血管内皮生长因子C。已观察到该位点与上游PIR(GeneID 8544)位点之间的读出转录。[ RefSeq，FEB 2011 ]提供。