FITC标记的9号染色体开放阅读框3抗体
产品名称： FITC标记的9号染色体开放阅读框3抗体
英文名称： Anti-C9orf3/FITC
产品编号： HZ-20376R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-C9orf3/FITC Conjugated antibody
FITC标记的9号染色体开放阅读框3抗体
| 英文名称 | Anti-C9orf3/FITC |
| 中文名称 | FITC标记的9号染色体开放阅读框3抗体 |
| 别 名 | Aminopeptidase O; AP O; APO; Chromosome 9 open reading frame 3;AMPO_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 94kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C9orf3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: C9orf3 is an aminopeptidase and belongs to the M1 family of metallopeptidases or gluzincins. Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. C9orf3 is able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway but not able to cleave angiotensin I and angiotensin II. It may play a role in the proteolytic processing of bioactive peptides in tissues where it is expressed. C9orf3 is predominantly expressed in pancreas, placenta, liver, testis and heart and at lower level in brain, lung and kidney. There are four named isoforms. Function: Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. Subcellular Location: Cytoplasm (Potential). Tissue Specificity: Predominantly expressed in pancreas, placenta, liver, testis and heart. Expressed at lower level in brain, lung and kidney. Similarity: Belongs to the peptidase M1 family. Database links: Entrez Gene: 84909 Human SwissProt: Q8N6M6 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
C9OFF3是一种氨肽酶，属于金属肽酶或谷氨酸锌的M1家族。氨基肽酶催化肽或蛋白质底物的N端氨基酸残基的水解。C9orf3能够裂解血管紧张素III产生血管紧张素IV，血管紧张素IV是肾素-血管紧张素途径的生物活性肽，但不能裂解血管紧张素I和血管紧张素II。它可能在表达生物活性肽的组织的蛋白水解过程中起作用。C9orf3主要表达于胰腺、胎盘、肝脏、睾丸和心脏，在脑、肺和肾脏中表达较低。有四个命名的异构体。