FITC标记的TIP41样蛋白抗体
产品名称: FITC标记的TIP41样蛋白抗体
英文名称: Anti-TIPRL/FITC
产品编号: HZ-
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-TIPRL/FITC Conjugated antibody
FITC标记的TIP41样蛋白抗体
英文名称 | Anti-TIPRL/FITC |
中文名称 | FITC标记的TIP41样蛋白抗体 |
别 名 | 1810011K17Rik; dJ69E11.3; MGC3794; Putative MAPK activating protein PM10; Putative MAPK-activating protein PM10; RP1-69E11.1; Tip; TIP41; TIP41-like protein; tiprl; TIPRL_HUMAN; TOR Signaling Pathway Regulator like; Type 2A-interacting protein. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 信号转导 激酶和磷酸酶 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 31kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 2mg/1ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TIPRL |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010] Function: May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. Subunit: Isoform 1 interacts with PPP2CA. Isoform 2 does notinteract with PPP2CA. Interacts with PPP2CB, PPP4C and PPP6C.Interacts with IGBP1; the interaction is dependent on PPP2CA.Associates with a protein phosphatase 2A PP2A(C):alpha-4 complex. Subcellular Location: Cytoplasm. Similarity: Belongs to the TIP41 family. Database links: Entrez Gene: 261726 Human Entrez Gene: 226591 Mouse Entrez Gene: 360869 Rat Omim: 611807 Human SwissProt: O75663 Human SwissProt: Q8BH58 Mouse SwissProt: A2VCX1 Rat Unigene: 209431 Human Unigene: 21520 Mouse Unigene: 56867 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
TIPRL是蛋白磷酸酶-2A(PP2A)的抑制性调节剂(见PPP2CA;MIM 176915)、PP4(见PPP4C;MIM 602035)和P26(见PPP6C;MIM 612725)(McConnell等,2007[PubMed 17384681])。