FITC标记的细胞骨架4.1蛋白家族DAL1抗体
产品名称： FITC标记的细胞骨架4.1蛋白家族DAL1抗体
英文名称： Anti-DAL1/ EPB41L3/FITC
产品编号： HZ-20463R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围：
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-DAL1/ EPB41L3/FITC Conjugated antibody
FITC标记的细胞骨架4.1蛋白家族DAL1抗体
| 英文名称 | Anti-DAL1/ EPB41L3/FITC |
| 中文名称 | FITC标记的细胞骨架4.1蛋白家族DAL1抗体 |
| 别 名 | Differentially expressed in adenocarcinoma of the lung protein 1; 4.1B; Band 4.1 like protein 3; DAL 1; DAL1; EPB41L3; Erythrocyte membrane protein band 4.1 like 3; HGNC:3380; KIAA0987; E41L3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 细胞骨架 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 96/120kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DAL1/ EPB41L3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: EPB41L3 is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. EPB41L3 is a member of the protein 4.1 superfamily, which encompasses structural proteins that play important roles in membrane processes via interactions with actin, spectrin, and the cytoplasmic domains of integral membrane proteins. The gene for EPB41L3 is thought to function as a tumor suppressor and localizes within chromosomal region 18p11.3, which is affected by loss of heterozygosity (LOH) in various adult tumors. Function: Critical growth regulator in the pathogenesis of meningiomas. Subunit: Interacts with CADM1. Subcellular Location: Cytoplasm, cytoskeleton Tissue Specificity: Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Similarity: ontains 1 FERM domain. Database links: Entrez Gene: 23136 Human Entrez Gene: 13823 Mouse Entrez Gene: 116724 Rat Omim: 605331 Human SwissProt: Q9Y2J2 Human SwissProt: Q9WV92 Mouse Unigene: 213394 Human Unigene: 131135 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
EPB41L3是一种肌动蛋白结合蛋白，最初被鉴定为在肺腺癌中表达下调的分子。EPB41L3是蛋白4.1超家族的成员，它包含结构蛋白，通过与肌动蛋白、光谱蛋白和整体膜蛋白的胞浆结构域的相互作用，在膜过程中发挥重要作用。EPB41L3基因被认为是一种肿瘤抑制基因，位于染色体区域18p11.3内，受多种成人肿瘤中杂合性缺失（LOH）的影响。