Anti-DPY19L2抗体-抗体-抗体-生物在线
Anti-DPY19L2抗体

Anti-DPY19L2抗体

商家询价

产品名称: Anti-DPY19L2抗体

英文名称: DPY19L2

产品编号: YB--8291R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-DPY19L2抗体

产品编号 YB-8291R
英文名称 DPY19L2
中文名称 DPY19L2蛋白抗体
别    名 D19L2_HUMAN; dpy 19 like 2; dpy 19 like 2 (C. elegans); Dpy 19 like protein 2; Dpy-19-like protein 2; dpy19; DPY19L2; FLJ32949; FLJ36166; Protein dpy 19 homolog 2; Protein dpy-19 homolog 2.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  发育生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 87kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DPY19L2:101-200/758 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Required during spermatogenesis for sperm head elongation and acrosome formation.

Function:
Required during spermatogenesis for sperm head elongation and acrosome formation. 

Subunit:
Membrane; Multi-pass membrane protein (Potential). 

Subcellular Location:
Involvement in disease:Defects in DPY19L2 are a cause of globozoospermia (GLOBZOOS) . An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome. In the most severe cases the acrosome is totally absent. Globozoospermia is also characterized by abnormal nuclear shape as well as abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of GLOBZOOS.

Tissue Specificity:
Widely expressed with high expression in testis.

DISEASE:
Defects in DPY19L2 are the cause of spermatogenic failure type 9 (SPGF9) [MIM:613958]. An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome, which can be totally absent in most severe cases. Additional features are an abnormal nuclear shape and abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of SPGF9. 

Similarity:
Belongs to the dpy-19 family. 

SWISS:
Q6NUT2

Gene ID:
283417

Database links:

Entrez Gene: 283417 Human

Entrez Gene: 320752 Mouse

SwissProt: Q6NUT2 Human

SwissProt: P0CW70 Mouse

Unigene: 533644 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications