Anti-Properdin抗体
产品名称: Anti-Properdin抗体
英文名称: Properdin
产品编号: YB--8306R
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
- 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 183****2235
- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-Properdin抗体
产品编号 | YB-8306R |
英文名称 | Properdin |
中文名称 | P因子/备解素抗体 |
别 名 | BFD; CFP; Complement factor P; Complement factor properdin; Factor P; PFC; PFD; PROP_HUMAN; Properdin; Properdin P factor complement. |
规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Rabbit, |
产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 48kDa |
细胞定位 | 分泌型蛋白 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Properdin:401-469/469 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Involvement in disease:Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). Function: A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Subcellular Location: Secreted DISEASE: Defects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). Similarity: Contains 6 TSP type-1 domains. SWISS: P27918 Gene ID: 5199 Database links: Entrez Gene: 5199 Human Entrez Gene: 18636 Mouse Entrez Gene: 299314 Rat Omim: 300383 Human SwissProt: P27918 Human SwissProt: P11680 Mouse Unigene: 53155 Human Unigene: 3064 Mouse Unigene: 204119 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |