Anti-Proteasome 19S S5A抗体-抗体-抗体-生物在线
Anti-Proteasome 19S S5A抗体

Anti-Proteasome 19S S5A抗体

商家询价

产品名称: Anti-Proteasome 19S S5A抗体

英文名称: Proteasome 19S S5A

产品编号: YB--8322R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-Proteasome 19S S5A抗体

产品编号 YB-8322R
英文名称 Proteasome 19S S5A
中文名称 26S蛋白酶调节亚型S5a抗体
别    名 26S protease subunit S5a; 26S proteasome non ATPase regulatory subunit 4; 26S proteasome non-ATPase regulatory subunit 4; 26S proteasome regulatory subunit rpn10; 26S proteasome regulatory subunit S5A; AF 1; AF; AF1; Antisecretory factor 1; ASF; DS5a; MCB 1; MCB1; Multiubiquitin chain binding protein; Multiubiquitin chain-binding protein; Prosome macropain; Proteasome (Prosome macropain) 26S subunit non ATPase 4; Proteasome 26S non ATPase subunit 4; Proteasome 26S subunit non ATPase 4; PSMD 4; PSMD4; PSMD4_HUMAN; pUB R5; pUBR5; Rpn 10; Rpn10; S5A; S5a/antisecretory factor protein.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Proteasome 19S S5A:101-200/377 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.

Function:
Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion. 

Subunit:
The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively. Directly interacts with NUB1. Interacts with SQSTM1. Interacts with UBQLN4. Interacts with UBE3A. 

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR. 

Similarity:
Belongs to the proteasome subunit S5A family. 
Contains 2 UIM (ubiquitin-interacting motif) repeats. 
Contains 1 VWFA domain. 

SWISS:
P55036

Gene ID:
5710

Database links:

Entrez Gene: 5710 Human

Entrez Gene: 19185 Mouse

Entrez Gene: 83499 Rat

Omim: 601648 Human

SwissProt: P55036 Human

SwissProt: O35226 Mouse

Unigene: 505059 Human

Unigene: 2261 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications