Anti-FBXL3抗体-抗体-抗体-生物在线
Anti-FBXL3抗体

Anti-FBXL3抗体

商家询价

产品名称: Anti-FBXL3抗体

英文名称: FBXL3

产品编号: YB--8467R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-FBXL3抗体

产品编号 YB-8467R
英文名称 FBXL3
中文名称 FBXL3蛋白抗体
别    名 F box and leucine rich repeat protein 3; F box and leucine rich repeat protein 3A; F box protein Fbl3a; F-box and leucine-rich repeat protein 3A; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; FBL3; FBL3A; Fbxl3; FBXL3_HUMAN; FBXL3A.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXL3:151-250/428 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.

Function:
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation. 

Subunit:
Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with CRY1 and CRY2. 

Subcellular Location:
Nucleus. Cytoplasm. Predominantly nuclear.

Tissue Specificity:
Widely expressed.

Similarity:
Contains 1 F-box domain. 
Contains 7 LRR (leucine-rich) repeats. 

SWISS:
Q9UKT7

Gene ID:
26224

Database links:

Entrez Gene: 26224 Human

Entrez Gene: 50789 Mouse

Entrez Gene: 306129 Rat

Omim: 605653 Human

SwissProt: Q9UKT7 Human

SwissProt: Q8C4V4 Mouse

Unigene: 508284 Human

Unigene: 214746 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications