Anti-PDZK3抗体-抗体-抗体-生物在线
Anti-PDZK3抗体

Anti-PDZK3抗体

商家询价

产品名称: Anti-PDZK3抗体

英文名称: PDZK3

产品编号: YB--9037R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-PDZK3抗体

产品编号 YB-9037R
英文名称 PDZK3
中文名称 前列腺癌激活蛋白抗体
别    名 Activated in prostate cancer protein; AIPC; KIAA0300; Likely ortholog of rat plakophilin related armadillo repeat protein interacting PDZ protein antibody PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain containing protein 2; PDZ domain containing protein 3; PDZD2; PDZK 2; PDZK2; PDZK-2; PDZK 3; PDZK3; PDZK-3; PIN1; Plakophilin related armadillo repeat protein interacting PDZ protein like; Rat plakophilin related armadillo repeat protein interacting PDZ protein like; PDZD2_HUMAN.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 310kDa
细胞定位 细胞核 细胞浆 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDZK3:801-900/2839 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. PDZK3 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, the PDZK3 gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Subunit:
Interacts with SCN10A, CTNND2 and PKP4 (By similarity). 

Subcellular Location:
Cytoplasmic, Endoplasmic reticulum, Nuclear and Secreted

Tissue Specificity:
Isoform 2 is expressed (at protein level) in prostate and many prostate tumors. 

Post-translational modifications:
A secreted form is produced by caspase-mediated proteolytic cleavage (By similarity).

Similarity:
Contains 6 PDZ (DHR) domains. 

SWISS:
O15018

Gene ID:
23037

Database links:

Entrez Gene: 23037 Human

Entrez Gene: 68070 Mouse

Entrez Gene: 65034 Rat

Omim: 610697 Human

SwissProt: O15018 Human

SwissProt: Q9QZR8 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications