Anti-Protein Z抗体-抗体-抗体-生物在线
Anti-Protein Z抗体

Anti-Protein Z抗体

商家询价

产品名称: Anti-Protein Z抗体

英文名称: Protein Z

产品编号: YB--9513R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Protein Z抗体

产品编号 YB-9513R
英文名称 Protein Z
中文名称 蛋白Z抗体
别    名 Protein Z, vitamin K dependent plasma glycoprotein; PROZ; PROZ_HUMAN; PZ antibody Vitamin K-dependent protein Z.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 心血管  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Protein Z:301-400/400 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].

Function:
Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids. 

Subunit:
Interacts with SERPINA10.

Subcellular Location:
Secreted

Tissue Specificity:
Plasma

Post-translational modifications:
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains (By similarity). 

Similarity:
Belongs to the peptidase S1 family. 
Contains 2 EGF-like domains. 
Contains 1 Gla (gamma-carboxy-glutamate) domain. 
Contains 1 peptidase S1 domain.

SWISS:
P22891

Gene ID:
8858

Database links:

Entrez Gene: 8858 Human

Omim: 176895 Human

SwissProt: P22891 Human

Unigene: 1011 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications