Anti-Synaptogyrin 1抗体-抗体-抗体-生物在线
Anti-Synaptogyrin 1抗体

Anti-Synaptogyrin 1抗体

商家询价

产品名称: Anti-Synaptogyrin 1抗体

英文名称: Synaptogyrin 1

产品编号: YB--11372R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Synaptogyrin 1抗体

产品编号 YB-11372R
英文名称 Synaptogyrin 1
中文名称 神经细胞囊泡循环蛋白1抗体
别    名 SNG1_HUMAN;Synaptogyrin-1;Syngr1.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synaptogyrin 1:51-150/580 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal isoforms (Synaptogyrin-1 and -3) and one ubiquitous isoform (Synaptogyrin-2). Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as cellugyrin, has a tyrosine phosphorylated C-terminal cytoplasmic tail and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. Synaptogyrin-4 is a 234 amino acid protein encoded by the SYNGR4 gene.

Function:
Involved in the regulation of short-term and long-term synaptic plasticity.

Subcellular Location:
Membrane; Multi-pass membrane protein. Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Similarity:
Belongs to the synaptogyrin family.
Contains 1 MARVEL domain.

SWISS:
O43759 

Gene ID:
9145 

Database links:

Entrez Gene: 610027 Dog

Entrez Gene: 9145 Human

Entrez Gene: 20972 Mouse

Entrez Gene: 100626046 Pig

Entrez Gene: 100427479 Rhesus monkey

Omim: 603925 Human

SwissProt: O43759 Human

SwissProt: O55100 Mouse

SwissProt: Q5R703 Orangutan



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

囊泡循环蛋白,Synaptogyrin又称p29,是均一分布于神经系统的突触囊泡蛋白,在神经元及神经内分泌细胞高度表达,它是酪氨酸激酶的一个重要的囊泡相关底物。synaptogyrin为多基因家族编码,异构体的cDNA序列同源性为32%~46%。人的囊泡循环蛋白 cDNA有一阅读框架,编码234个氨基酸,分子量约25,683Da,有四个跨膜域,N端与C端朝向囊泡的胞质面,无糖基化位点,蛋白分子胞浆尾的氨基酸序列与Syp有74%的同源性