Anti-Synaptogyrin 1抗体
产品名称: Anti-Synaptogyrin 1抗体
英文名称: Synaptogyrin 1
产品编号: YB--11372R
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
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- 邮编 : 200612
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Anti-Synaptogyrin 1抗体
产品编号 | YB-11372R |
英文名称 | Synaptogyrin 1 |
中文名称 | 神经细胞囊泡循环蛋白1抗体 |
别 名 | SNG1_HUMAN;Synaptogyrin-1;Syngr1. |
规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 细胞生物 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Synaptogyrin 1:51-150/580 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal isoforms (Synaptogyrin-1 and -3) and one ubiquitous isoform (Synaptogyrin-2). Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as cellugyrin, has a tyrosine phosphorylated C-terminal cytoplasmic tail and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. Synaptogyrin-4 is a 234 amino acid protein encoded by the SYNGR4 gene. Function: Involved in the regulation of short-term and long-term synaptic plasticity. Subcellular Location: Membrane; Multi-pass membrane protein. Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Similarity: Belongs to the synaptogyrin family. Contains 1 MARVEL domain. SWISS: O43759 Gene ID: 9145 Database links: Entrez Gene: 610027 Dog Entrez Gene: 9145 Human Entrez Gene: 20972 Mouse Entrez Gene: 100626046 Pig Entrez Gene: 100427479 Rhesus monkey Omim: 603925 Human SwissProt: O43759 Human SwissProt: O55100 Mouse SwissProt: Q5R703 Orangutan Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 囊泡循环蛋白,Synaptogyrin又称p29,是均一分布于神经系统的突触囊泡蛋白,在神经元及神经内分泌细胞高度表达,它是酪氨酸激酶的一个重要的囊泡相关底物。synaptogyrin为多基因家族编码,异构体的cDNA序列同源性为32%~46%。人的囊泡循环蛋白 cDNA有一阅读框架,编码234个氨基酸,分子量约25,683Da,有四个跨膜域,N端与C端朝向囊泡的胞质面,无糖基化位点,蛋白分子胞浆尾的氨基酸序列与Syp有74%的同源性 |