Anti-IL-17F抗体-抗体-抗体-生物在线
Anti-IL-17F抗体

Anti-IL-17F抗体

商家询价

产品名称: Anti-IL-17F抗体

英文名称: IL-17F

产品编号: YB--7333R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

Anti-IL-17F抗体

产品编号 YB-7333R
英文名称 IL-17F
中文名称 白介素-17F抗体
别    名 Interleukin 17F;Cytokine ML-1;IL-17F,IL17F_MOUSE;Interleukin-17F;CANDF6;ML1.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  心血管  生长因子和激素  t-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat, 
产品应用 WB=1:500-2000 ELISA=1:500-1000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-17F:51-150/161 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]

Function:
Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.

DISEASE:
Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6) [MIM:613956]. CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.

Similarity:
Belongs to the IL-17 family.

SWISS:
Q7TNI7

Gene ID:
257630

Database links:
Entrez Gene: 257630 Mouse

Entrez Gene: 301291 Rat

SwissProt: Q7TNI7 Mouse

SwissProt: Q5BJ95 Rat

Unigene: 222807 Mouse

Unigene: 34022 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications