Anti-P27 Polyclonal Antibody
产品名称: Anti-P27 Polyclonal Antibody
英文名称: Anti-P27 Polyclonal Antibody
产品编号: K106720P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2024-01-22T15:19:33
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073
- 传真 :
- 邮箱 : 3193328036@qq.com
Anti-P27 Polyclonal Antibody
品牌:solarbio | 货号:K106720P
英文名称 | Anti-P27 Polyclonal Antibody |
---|---|
别名 | CDKN1B;CDKN4;KIP1;MEN1B;MEN4;P27;KIP1;P27KIP1 |
应用 | IHC |
稀释比例 | IHC 1:50-200. |
交叉反应 | Human |
蛋白分子量 | 22kDa |
Gene ID | 1027 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human P27 |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human P27 |
Subcellular Locations | Nucleus |
Swiss Prot | P46527 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4) |