Anti-Natriuretic Peptide Receptor A/FITC Conjugated抗体
产品名称: Anti-Natriuretic Peptide Receptor A/FITC Conjugated抗体
英文名称: Anti-Natriuretic Peptide Receptor A/FITC
产品编号: YB--7517R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
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- 邮编 : 200612
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Anti-Natriuretic Peptide Receptor A/FITC Conjugated抗体
产品编号 | YB-7517R-FITC |
英文名称 | Anti-Natriuretic Peptide Receptor A/FITC |
中文名称 | FITC标记的利钠肽受体A抗体 |
别 名 | NPRA; ANP A; ANP-A; ANPa; ANPR-A; ANPRA; ANPRA_HUMAN; Atrial natriuretic peptide A type receptor; Atrial natriuretic peptide receptor 1; Atrial natriuretic peptide receptor A; Atrial natriuretic peptide receptor type A; Atrionatriuretic peptide receptor A; GC A; GC-A; Guanylate cyclase A; Guanylate cyclase; GUC2A; GUCY2A; Natriuretic peptide A type receptor; Natriuretic peptide receptor A/guanylate cyclase A; NPR 1; NPR A; NPR-A; NPR1; NPRA. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 心血管 细胞生物 信号转导 G蛋白偶联受体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 113kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Natriuretic Peptide Receptor A |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009] Function: Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. Subunit: Homodimer. Subcellular Location: Membrane; Single-pass type I membrane protein. Post-translational modifications: Phosphorylation of the protein kinase-like domain is required for full activation by ANP. Similarity: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 1 guanylate cyclase domain. Contains 1 protein kinase domain. Database links: Entrez Gene: 4881 Human Entrez Gene: 24603 Rat Omim: 108960 Human SwissProt: P16066 Human SwissProt: P18910 Rat Unigene: 490330 Human Unigene: 10463 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |