Anti-SPON1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-SPON1/FITC Conjugated抗体

Anti-SPON1/FITC Conjugated抗体

商家询价

产品名称: Anti-SPON1/FITC Conjugated抗体

英文名称: Anti-SPON1/FITC

产品编号: YB--7520R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-SPON1/FITC Conjugated抗体

产品编号 YB-7520R-FITC
英文名称 Anti-SPON1/FITC
中文名称 FITC标记的细胞外基质底物反应蛋白1抗体
别    名 F spondin; F spondin extracellular matrix protein; FSPO; KIAA0762; MGC10724; SPON 1; spondin 1 (f spondin) extracellular matrix protein; Spondin 1; Spondin 1 extracellular matrix protein; Spondin 1 precursor; Spondin1; Vascular smooth muscle cell growth promoting factor; VSGP; VSGP/F spondin.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 86kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPON1/F spondin
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SPON1 is a member of a subgroup of the thrombospondin type 1 (TSR) class molecules, defined by two domains of homology, the FS1/FS2 and TSR domains. The TSRs of SPON1 proteins are typical of class 2 TSRs. SPON1, which is similar to thrombospondin, is a extracellular matrix attached molecule that promotes neurite outgrowth and inhibits angiogenesis. Analysis of gain and loss of function experiments reveal that SPON1 is required for accurate pathfinding of embryonic axons, and plays a dual role in patterning axonal trajectories. It promotes the outgrowth of commissural and inhibits the outgrowth of motor axons, and has also been implicated in inflammatory processes in the nervous system.

Subunit:
Binds to the central extracellular domain of APP and inhibits beta-secretase cleavage of APP.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Highest expression in lung, lower expression in brain, heart, kidney, liver and testis, and lowest expression in pancreas, skeletal muscle and ovary. Not expressed in spleen.

Similarity:
Contains 1 reelin domain.
Contains 1 spondin domain.
Contains 6 TSP type-1 domains.

Database links:
 

UniProtKB/Swiss-Prot: Q9HCB6.2



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications