Anti-SART3/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-SART3/FITC Conjugated抗体

Anti-SART3/FITC Conjugated抗体

商家询价

产品名称： Anti-SART3/FITC Conjugated抗体

英文名称： Anti-SART3/FITC

产品编号： YB--7009R-FITC

产品价格： null

产品产地： 中国/美国

品牌商标： Ybscience

更新时间： 2023-08-17T10:29:50

使用范围： 科研使用

上海钰博生物科技有限公司
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 Anti-SART3/FITC Conjugated抗体

产品编号 YB-7009R-FITC
英文名称 Anti-SART3/FITC
中文名称 FITC标记的T淋巴细胞识别的鳞状细胞癌SART3抗体
别    名 p110(nrb); SART3; SART-3; Tat interacting protein of 110 kDa; TIP110; SART3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细菌及病毒  t-淋巴细胞  肿瘤细胞生物标志物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 110kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SART3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
RelevanceSART3 regulates Tat transactivation activity through direct interaction. It may be a cellular factor for HIV1 gene expression and viral replication.

Subunit:
Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs. Interacts with HIV-1 Tat. Interacts with EIF2C1 and EIF2C2.

Subcellular Location:
Cytoplasm. Nucleus speckle. Note=Localized in speckles. Expressed in the nucleus of all of the malignant tumor cell lines tested and the majority of cancer tissues with various histologies, including squamous cell carcinomas (SCC), adenocarcinomas, melanomas and leukemias cells. However, this protein is undetectable in the nucleus of any cell lines of nonmalignant cells or normal tissues, except for the testis. Expressed in the cytoplasm of all the proliferating cells, including normal and malignant cells, but not in normal tissues, except for the testis and the fetal liver.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Contains 8 HAT repeats. 
Contains 2 RRM (RNA recognition motif) domains.

Database links:
 

UniProtKB/Swiss-Prot: Q15020.1



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications