Anti-GABRA5/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-GABRA5/FITC Conjugated抗体

Anti-GABRA5/FITC Conjugated抗体

商家询价

产品名称: Anti-GABRA5/FITC Conjugated抗体

英文名称: Anti-GABRA5/FITC

产品编号: YB--6708R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-GABRA5/FITC Conjugated抗体

产品编号 YB-6708R-FITC
英文名称 Anti-GABRA5/FITC
中文名称 FITC标记的γ1氨基丁酸受体α5/GABRα5抗体
别    名 GBRA5_HUMAN; GAA 5; GAA5; GABRA 5; GABRA5; Gamma aminobutyric acid GABA A receptor alpha 5; Gamma aminobutyric acid GABA A receptor alpha 5 precursor; Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABRA5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non coding first exons have been described.

Function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Subunit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily.

Database links:

Entrez Gene: 523515 Cow

Entrez Gene: 2558 Human

Entrez Gene: 110886 Mouse

Entrez Gene: 29707 Rat

Omim: 137142 Human

SwissProt: Q08E50 Cow

SwissProt: P31644 Human

SwissProt: Q8BHJ7 Mouse

SwissProt: P19969 Rat

Unigene: 24969 Human

Unigene: 273114 Mouse

Unigene: 10368 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications