Anti-CH25H/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-CH25H/FITC Conjugated抗体

Anti-CH25H/FITC Conjugated抗体

商家询价

产品名称: Anti-CH25H/FITC Conjugated抗体

英文名称: Anti-CH25H /FITC

产品编号: YB--23620R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-CH25H/FITC Conjugated抗体

产品编号 YB-23620R-FITC
英文名称 Anti-CH25H /FITC
中文名称 FITC标记的胆固醇25羟化酶抗体
别    名 C25H; CH25H; Cholesterol 25 hydroxylase; Cholesterol 25 monooxygenase; EC 1.14.99.38; EC=1.14.99.38; h25OH; CH25H_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  激酶和磷酸酶  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CH25H
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.

Function:
CH25H is involved in cholesterol and lipid metabolism and catalyses the formation of 25-hydroxycholesterol from cholesterol, leading to repression of cholesterol biosynthetic enzymes. It may play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing.

Subcellular Location:
Endoplasmic reticulum membrane

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the sterol desaturase family.

Database links:

Entrez Gene: 9023 Human

Entrez Gene: 12642 Mouse

Entrez Gene: 309527 Rat

Omim: 604551 Human

SwissProt: O95992 Human

SwissProt: Q9Z0F5 Mouse

SwissProt: Q4QQV7 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications