Anti-DNAJC10/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-DNAJC10/FITC Conjugated抗体

Anti-DNAJC10/FITC Conjugated抗体

商家询价

产品名称: Anti-DNAJC10/FITC Conjugated抗体

英文名称: Anti-DNAJC10/FITC

产品编号: YB--1276R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-DNAJC10/FITC Conjugated抗体

产品编号 YB-1276R-FITC
英文名称 Anti-DNAJC10/FITC
中文名称 FITC标记的Erdj5/DNAJC10蛋白抗体
别    名 DNAJC10; DnaJ (Hsp40) homolog subfamily C member 10; DnaJ homolog subfamily C member 10; DNAJC 10; ER resident protein ERdj5; ERdj 5; ERdj5; J domain containing protein disulfide isomerase like protein; JPDI; Macrothioredoxin; MGC104194; MTHr; DJC10_HUMAN; DnaJ homolog subfamily C member 10; ER-resident protein ERdj5; Macrothioredoxin; MTHr.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAJC10
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]. 

Function:
This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. May act as a co-chaperone for HSPA5.

Subunit:
Interacts with HSPA5 via its J domain.

Subcellular Location:
Secreted (Potential). Endoplasmic reticulum lumen.

Similarity:
Contains 1 J domain.
Contains 4 thioredoxin domains.

Database links:

Entrez Gene: 54431 Human

Omim: 607987 Human

SwissProt: Q8IXB1 Human

Unigene: 516632 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

ERdj5酶的功能就像一个“质检员”,能够识别出那些存在缺陷的蛋白质,并在这些蛋白质“上岗”前将其降解掉。由于降解的是蛋白质,而不是变异本身,因此过降解导致了变异型蛋白质CFTR降解,出现囊肿性纤维化病理改变(如:遗传性胰腺疾病)