Anti-TSLP/FITC Conjugated抗体
产品名称: Anti-TSLP/FITC Conjugated抗体
英文名称: Anti-TSLP/FITC
产品编号: YB--0449R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
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- 邮编 : 200612
- 所在区域 : 上海
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- 邮箱 : shybio@126.com
Anti-TSLP/FITC Conjugated抗体
产品编号 | YB-0449R-FITC |
英文名称 | Anti-TSLP/FITC |
中文名称 | FITC标记的胸腺基质淋巴细胞生成素-1抗体 |
别 名 | Thymic stromal lymphopoietin isoform 1; Thymic stromal lymphopoietin; Thymic stromal lymphopoietin protein TSLP; TSLP protein; TSLP_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 细胞因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 15kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TSP-1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Thymic stromal lymphopoietin (TSLP) is a novel cytokine that was found to promote the development of murine B cells in vitro. This protein, which is expressed in a number of tissues including heart, liver and prostate, prevented apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ-3. Anti-interleukin (IL)-7 receptor antibodies (Abs) neutralized this effect indicating that TSLP binds to at least part of the IL-7 receptor complex. TSLP induced phosphorylation of signal transducer and activator of transcription (STAT)-5. Function: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Subunit: Interacts with a receptor composed of CRLF2 and IL7R. Subcellular Location: Secreted. Tissue Specificity: Expressed in a number of tissues including heart, liver and prostate. Database links: Entrez Gene: 85480 Human Entrez Gene: 53603 Mouse Entrez Gene: 688621 Rat Omim: 607003 Human SwissProt: Q969D9 Human SwissProt: Q9JIE6 Mouse Unigene: 389874 Human Unigene: 143716 Mouse Unigene: 201724 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胸腺基质淋巴细胞生成素-1(胸腺基质细胞分泌的淋巴细胞生成素-1) 为一种新型促进生长的细胞因子——胸腺基质淋巴蛋白(TSLP)可以引发炎症反应, 这种炎症反应可以引起很多过敏性疾病和哮*。 TSLP可能是过敏性疾病最重要的引发剂,已得到科学家的重视,如果证实了 TSLP是一种起始因子,抑制TSLP可以有效地治疗哮*和其它过敏性疾病 |