Anti-TIGAR/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-TIGAR/FITC Conjugated抗体

Anti-TIGAR/FITC Conjugated抗体

商家询价

产品名称: Anti-TIGAR/FITC Conjugated抗体

英文名称: Anti-TIGAR/FITC

产品编号: YB--0640R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-TIGAR/FITC Conjugated抗体

产品编号 YB-0640R-FITC
英文名称 Anti-TIGAR/FITC
中文名称 FITC标记的TIGAR蛋白抗体
别    名 TP53-induced glycolysis and apoptosis-regulator; C12ORF5; chromosome 12 open reading frame 5; TP53 induced glycolysis and apoptosis regulato; TIGAR_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIGAR
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008]

Function:
Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53.

Subunit:
Monomer.

Similarity:
Belongs to the phosphoglycerate mutase family.

Database links:

Entrez Gene: 57103 Human

Omim: 610775 Human

SwissProt: Q9NQ88 Human

Unigene: 504545 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

TIGAR为TP53诱导糖酵解和凋亡调节因子
TIGAR的表达可以调整对p53的凋亡应答,主要用于肿瘤方面的研究