Anti-Sema3A/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Sema3A/FITC Conjugated抗体

Anti-Sema3A/FITC Conjugated抗体

商家询价

产品名称: Anti-Sema3A/FITC Conjugated抗体

英文名称: Anti-Sema3A/FITC

产品编号: YB--1121R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-Sema3A/FITC Conjugated抗体

产品编号 YB-1121R-FITC
英文名称 Anti-Sema3A/FITC
中文名称 FITC标记的臂板蛋白3A抗体
别    名 Semaphorin 3A; Semaphorin-3A; Semaphorin-3A precursor; Semaphorin3A; SemD; Sema 3A; SEM3A_MOUSE; Coll 1; Coll1; Hsema I; Hsema III; sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3A; Sema III; SEMA1; SEMA1-PEN; SEMA3A; SEMAD; SEMAIII; SEMAL; Semaphorin III; Semaphorin like growth cone guidance homolog of chick collapsin; Semaphorin III; Semaphorin-D; Sema D.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 86kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Sema3A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Function:
Plays a role in growth cones guidance. May function to pattern sensory projections by selectively repelling axons that normally terminate dorsally. Involved in the development of the olfactory system and in neuronal control of puberty.

Subunit:
Interacts with PXND1.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed at relatively high levels in brain and muscle, moderate levels in lung, bursa, and heart and virtually absent in liver. Collapsin-1, -2, -3, and -5 bind to overlapping but distinct axon tracts.

Similarity:
Belongs to the semaphorin family. 
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. 
Contains 1 PSI domain. 
Contains 1 Sema domain.

Database links:

Entrez Gene: 10371 Human

Entrez Gene: 20346 Mouse

Entrez Gene: 29751 Rat

Omim: 603961 Human

SwissProt: Q14563 Human

SwissProt: O08665 Mouse

SwissProt: Q5BL08 Mouse

SwissProt: Q63548 Rat

Unigene: 252451 Human

Unigene: 44410 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications