Anti-PLGF/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-PLGF/FITC Conjugated抗体

Anti-PLGF/FITC Conjugated抗体

商家询价

产品名称: Anti-PLGF/FITC Conjugated抗体

英文名称: Anti-PLGF/FITC

产品编号: YB--0280R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-PLGF/FITC Conjugated抗体

产品编号 YB-0280R-FITC
英文名称 Anti-PLGF/FITC
中文名称 FITC标记的胎盘生长因子抗体
别    名 Placenta growth factor; PGF; PGFL; PIGF; Placental growth factor vascular endothelial growth factor related protein; PlGF 2; PLGF; PlGF2; PLGF_MOUSE; Vascular endothelial growth factor related protein.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  生长因子和激素  转录调节因子  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat, Pig, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse PLGF
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

Function:
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner.

Subunit:
Antiparallel homodimer; disulfide-linked. Also found as heterodimer with VEGFA/VEGF.

Subcellular Location:
Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.

Tissue Specificity:
While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the PDGF/VEGF growth factor family.

Database links:

Entrez Gene: 5228 Human

Entrez Gene: 18654 Mouse

Entrez Gene: 94203 Rat

Omim: 601121 Human

SwissProt: P49763 Human

SwissProt: P49764 Mouse

SwissProt: Q63434 Rat

Unigene: 252820 Human

Unigene: 4809 Mouse

Unigene: 6960 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

PLGF胎盘生长因子是血管生长因子家族成员之一(又称:胎盘型血管内皮细胞生长因子),是动脉粥样硬化斑块不稳定的主要炎性激活物,因此它可作为ACS患者风险预测的生物学标志物.尿胎盘生长因子水平可预测先兆子痫危险.研究人员发现,在疾病发作前的6到8周,先兆子痫患者尿液中的胎盘生长因子水平急剧下降,这种新的尿检方法使提前1到2个月预测先兆子痫成为可能。亦有研究人员正在从事胎盘生长因子与肺气肿,胃癌,肠癌等方面的研究