Anti-Orexin receptor 1+2/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Orexin receptor 1+2/FITC Conjugated抗体

Anti-Orexin receptor 1+2/FITC Conjugated抗体

商家询价

产品名称: Anti-Orexin receptor 1+2/FITC Conjugated抗体

英文名称: Anti-Orexin receptor 1+2/FITC

产品编号: YB--1095R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Orexin receptor 1+2/FITC Conjugated抗体

产品编号 YB-1095R-FITC
英文名称 Anti-Orexin receptor 1+2/FITC
中文名称 FITC标记的丘脑分泌素受体1+2/食欲素受体1+2抗体
别    名 Orexin Receptor 1 and 2; Orexin receptor 1 + 2; Orexin Receptor 2; HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1r; OX1R_HUMAN; Hcrtr2; Hypocretin (orexin) receptor 2; Hypocretin receptor 2; Hypocretin receptor type 2; Orexin receptor 2; Orexin receptor type 2; Ox-2-R; Ox2-R; Ox2r; OX2R_HUMAN.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  通道蛋白  细胞膜受体  内分泌病  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Orexin receptor 1/2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]

Function:
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 3061 Human

Entrez Gene: 230777 Mouse

Entrez Gene: 25593 Rat

Omim: 602392 Human

SwissProt: O43613 Human

SwissProt: P58307 Mouse

SwissProt: P56718 Rat

Unigene: 388226 Human

Unigene: 246595 Mouse

Unigene: 88262 Rat

Entrez Gene: 3062 Human

Entrez Gene: 387285 Mouse

Entrez Gene: 25605 Rat

Omim: 602393 Human

SwissProt: O43614 Human

SwissProt: P58308 Mouse

SwissProt: P56719 Rat

Unigene: 151624 Human

Unigene: 699147 Human

Unigene: 335300 Mouse

Unigene: 9893 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

食欲素受体(OXR)Orexin receptor—是一种G蛋白偶合受体. 下丘脑是调节饮食及能量平衡的中枢.学者认为:在下丘脑可促进食欲且来源于同一前体的两种新神经肽:食欲素A和B,它们可激活两种密切相关且与G蛋白偶联的细胞表面受体(OX1R,OX2R).含Orexin的神经细胞在下丘脑腹外侧呈对称的不连贯分布. 在饮食反馈调节中具有重要作用.食欲素与其它影响进食的神经肽之间存在错综复杂的关系.它在增加摄食、饮水、调节睡眠觉醒周期、生殖、体温、血压和感觉等方面有广泛作用