Anti-PACAP receptor/FITC Conjugated抗体
产品名称: Anti-PACAP receptor/FITC Conjugated抗体
英文名称: Anti-PACAP receptor/FITC
产品编号: YB--0198R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
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- 邮编 : 200612
- 所在区域 : 上海
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- 邮箱 : shybio@126.com
Anti-PACAP receptor/FITC Conjugated抗体
产品编号 | YB-0198R-FITC |
英文名称 | Anti-PACAP receptor/FITC |
中文名称 | FITC标记的腺苷酸环化酶激活肽受体1抗体 |
别 名 | ADCYAP1 R1; ADCYAP1R 1; PACAP-R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1; PAC 1; PAC1; PAC1R; PACAP R 1; PACAP1 R; PACAPR; PACAPRI; Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; Pituitary adenylate cyclase activating polypeptide receptor; Pituitary adenylate cyclase activating polypeptide type I receptor precursor; PACR_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 神经生物学 细胞膜受体 G蛋白偶联受体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 51kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from the middle of human PACAP R1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide belonging to the vasoactive intestinal polypeptide/glucagon/ secretin family. It is widely distributed in the body, and a variety of biological actions have been reported. Recent studies have shown that there is a family of PACAP receptors (PACAPRs), and two members of this family have been identified. This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract (By similarity). Belongs to the G-protein coupled receptor 2 family. Function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Subunit: Interacts (via N-terminal extracellular domain) with ADCYAP1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta. Similarity: Belongs to the G-protein coupled receptor 2 family. Database links: Entrez Gene: 117 Human Entrez Gene: 319095 Cow Entrez Gene: 11517 Mouse Entrez Gene: 24167 Rat Omim: 102981 Human SwissProt: Q29627 Cow SwissProt: P41586 Human SwissProt: P70205 Mouse SwissProt: P32215 Rat Unigene: 377783 Human Unigene: 44245 Mouse Unigene: 88408 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 生长因子和激素( Growth Factor and Hormones) PACAP 受体分为两个亚型,PACAP-1型受体对PACAP是特异性的,与PACAP的亲和力比VIP高100-1000倍,PACAP-II型受体与PACAP和VIP的亲和力相似,对二者无选择性。此抗体即为前者 |