Anti-C9orf127/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-C9orf127/FITC Conjugated抗体

Anti-C9orf127/FITC Conjugated抗体

商家询价

产品名称: Anti-C9orf127/FITC Conjugated抗体

英文名称: Anti-C9orf127/FITC

产品编号: YB--1065R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-C9orf127/FITC Conjugated抗体

产品编号 YB-1065R-FITC
英文名称 Anti-C9orf127/FITC
中文名称 FITC标记的鼻咽癌细胞相关基因6抗体
别    名 NGX6; 4930500O05Rik; C9orf127; MGC120460; NAG-5; NGX6; RGD1310012; RP11-112J3.10; TMEM8B; nasopharyngeal carcinoma; NPC associated gene 6; TMM8B_HUMAN; chromosome 9 open reading frame 127; NAG 5; Nasopharyngeal carcinoma expressed 6; Nasopharyngeal carcinoma related protein; Nasopharyngeal carcinoma-associated gene 6 protein; Protein NAG-5; Protein NGX6; RP11-112J3.10; RP11-112J3.10-001; TMEM8B; Transmembrane protein 8B .  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NGX6 N-terminus
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
NGX6 (nasopharyngeal carcinoma/NPC associated gene 6) may function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. [SUBUNIT] Isoform 2 (via its cytoplasmic part) interacts with EZR. [SUBCELLULAR LOCATION] Isoform 2: Cell membrane; Multi-pass membrane protein (Probable). Cytoplasm (Probable). Nucleus (Probable). Mitochondrion. Endoplasmic reticulum. Belongs to the NGX6 family.
The down-regulation of C9orf127 may be closely associated with tumorigenesis and metastasis of colorectal carcinoma. However, it may not contribute to the development and progression of gastric carcinoma. 

Function:
May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion.

Subunit:
Isoform 2 (via its cytoplasmic part) interacts with EZR.

Subcellular Location:
Cell membrane. Cytoplasm. Nucleus. Mitochondrion. Endoplasmic reticulum. Also detected in mitochondrion and endoplasmic reticulum.

Post-translational modifications:
Isoform 2 is N-glycosylated.

Similarity:
Belongs to the TMEM8 family.
Contains 1 EGF-like domain.

Database links:

Entrez Gene: 51754 Human

Entrez Gene: 100125302 Cow

Entrez Gene: 242409 Mouse

Entrez Gene: 313490 Rat

SwissProt: A6QLK4 Cow

SwissProt: A6NDV4 Human

SwissProt: B1AWJ5 Mouse

Unigene: 493808 Human

Unigene: 171489 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

NGX6是鼻咽癌发生和发展重要的相关蛋白,NGX-6作用于鼻咽癌细胞,抗体可用于鼻咽癌诊断。有学者认为:NGX6也表达在部分消化系统的肿瘤中