Anti-DGKZ/FITC Conjugated抗体
产品名称: Anti-DGKZ/FITC Conjugated抗体
英文名称: Anti-DGKZ/FITC
产品编号: YB--14301R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
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- 邮编 : 200612
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Anti-DGKZ/FITC Conjugated抗体
产品编号 | YB-14301R-FITC |
英文名称 | Anti-DGKZ/FITC |
中文名称 | FITC标记的甘油二酯激酶ζ/DGK-ζ抗体 |
别 名 | DAG kinase zeta; DAGK5; DAGK5 PEN; DAGK6; DGK ZETA; DGK-zeta; Dgkz; DGKZ_HUMAN; Diacylglycerol kinase zeta; Diglyceride kinase zeta; hDGKzeta. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 心血管 细胞生物 信号转导 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Guinea Pig, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 124kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DGKZ |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010] Function: Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity. Subcellular Location: Cytoplasm. Nucleus. Cell membrane. Tissue Specificity: Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle. Post-translational modifications: Phosphorylation of the MARCKS homology domain by PKC reduces nuclear accumulation of DGK-zeta. Similarity: Belongs to the eukaryotic diacylglycerol kinase family. Contains 2 ANK repeats. Contains 1 DAGKc domain. Contains 2 phorbol-ester/DAG-type zinc fingers. Database links: Entrez Gene: 8525 Human Entrez Gene: 423197 Chicken Entrez Gene: 483635 Dog Entrez Gene: 100050499 Horse Entrez Gene: 104418 Mouse Entrez Gene: 81821 Rat Omim: 601441 Human SwissProt: Q13574 Human SwissProt: Q80UP3 Mouse SwissProt: O08560 Rat Unigene: 502461 Human Unigene: 314923 Mouse Unigene: 11208 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |