Anti-NIPSNAP1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-NIPSNAP1/FITC Conjugated抗体

Anti-NIPSNAP1/FITC Conjugated抗体

商家询价

产品名称: Anti-NIPSNAP1/FITC Conjugated抗体

英文名称: Anti-NIPSNAP1/FITC

产品编号: YB--19252R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-NIPSNAP1/FITC Conjugated抗体

产品编号 YB-19252R-FITC
英文名称 Anti-NIPSNAP1/FITC
中文名称 FITC标记的NIPSNAP1蛋白抗体
别    名 NIPSNAP 1; Nipsnap homolog 1 (C. elegans); Protein NipSnap homolog 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  通道蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NIPSNAP1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

Function:
NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory. 

Subcellular Location:
Mitochondrial

Database links:

Entrez Gene: 8508 Human

Entrez Gene: 18082 Mouse

Entrez Gene: 360971 Rat

Omim: 603249 Human

SwissProt: Q9BPW8 Human

SwissProt: O55125 Mouse

Unigene: 173878 Human

Unigene: 293716 Mouse

Unigene: 103205 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications