Anti-SLC32A 1/FITC Conjugated抗体
产品名称: Anti-SLC32A 1/FITC Conjugated抗体
英文名称: Anti-SLC32A 1/FITC
产品编号: YB--10958R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
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Anti-SLC32A 1/FITC Conjugated抗体
产品编号 | YB-10958R-FITC |
英文名称 | Anti-SLC32A 1/FITC |
中文名称 | FITC标记的氨基丁酸转运蛋白VGAT抗体 |
别 名 | VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32 (GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 57kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SLC32A 1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure Function: Involved in the uptake of GABA and glycine into the synaptic vesicles. Subcellular Location: Cytoplasmic vesicle membrane; Multi-pass membrane protein. Tissue Specificity: Retina. Expressed throughout the horizontal cells or more specifically at the terminals. Similarity: Belongs to the amino acid/polyamine transporter 2 family. Database links: Entrez Gene: 140679 Human Entrez Gene: 22348 Mouse Entrez Gene: 83612 Rat SwissProt: Q9H598 Human SwissProt: O35633 Mouse SwissProt: O35458 Rat Unigene: 179080 Human Unigene: 143404 Mouse Unigene: 413854 Mouse Unigene: 10846 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |