Anti-SAMD8/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-SAMD8/FITC Conjugated抗体

Anti-SAMD8/FITC Conjugated抗体

商家询价

产品名称: Anti-SAMD8/FITC Conjugated抗体

英文名称: Anti-SAMD8/FITC

产品编号: YB--19376R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-SAMD8/FITC Conjugated抗体

产品编号 YB-19376R-FITC
英文名称 Anti-SAMD8/FITC
中文名称 FITC标记的SAMD8蛋白抗体
别    名 1110053F04Rik; 1700010P07Rik; FLJ25082; MGC118303; RP11-487I5.5; SMSr; Sphingomyelin synthase related; Sphingomyelin synthase related protein 1; Sterile alpha motif domain containing 8.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SAMD8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SAMD8 is a multi-pass membrane protein. It belongs to the sphingomyelin synthase family and contains 1 SAM (sterile alpha motif) domain. The function of the SAMD8 protein remains unknown. 

Function:
Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.

Similarity:
Belongs to the sphingomyelin synthase family.

Database links:

Entrez Gene: 142891 Human

Entrez Gene: 67630 Mouse

Entrez Gene: 305684 Rat

Omim: 611575 Human

SwissProt: Q96LT4 Human

SwissProt: Q9DA37 Mouse

SwissProt: Q641X0 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications