Anti-Prokineticin 1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Prokineticin 1/FITC Conjugated抗体

Anti-Prokineticin 1/FITC Conjugated抗体

商家询价

产品名称: Anti-Prokineticin 1/FITC Conjugated抗体

英文名称: Anti-Prokineticin 1/FITC

产品编号: YB--23740R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-Prokineticin 1/FITC Conjugated抗体

产品编号 YB-23740R-FITC
英文名称 Anti-Prokineticin 1/FITC
中文名称 FITC标记的内分泌腺衍生血管内皮生长因子抗体
别    名 Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor; Prokineticin1; Prokineticin 1; EG-VEGF; EG VEGF; EGVEGF; PROK1; EGVEGF; PK1; PRK1; PROK1_HUMAN; Black mamba toxin related protein; Endocrine gland derived vascular endothelial growth factor; Endocrine-gland-derived vascular endothelial growth factor; Mambakine; Prokineticin-1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  神经生物学  信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Dog, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9.7kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Prokineticin 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]

Function:
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. 

Subcellular Location:
Secreted. 

Tissue Specificity:
Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. 

Similarity:
Belongs to the AVIT (prokineticin) family. 

Database links:

Entrez Gene: 84432 Human

Entrez Gene: 246691 Mouse

Entrez Gene: 192205 Rat

Omim: 606233 Human

SwissProt: P58294 Human

SwissProt: Q14A28 Mouse

SwissProt: Q8R414 Rat

Unigene: 514793 Human

Unigene: 461353 Mouse

Unigene: 82757 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

EG-VEGF是先被发现的组织特异性促血管生成因子,与多种特定组织肿瘤的发生及演进相关,EG-VEGF多在卵巢、睾丸、肾上腺、胎盘等类固醇合成组织中高表达