Anti-RAD23B Monoclonal Antibody
产品名称: Anti-RAD23B Monoclonal Antibody
英文名称: Anti-RAD23B Monoclonal Antibody
产品编号: K000127M
产品价格: null
产品产地: 北京市通州区马驹桥
品牌商标: solarbio
更新时间: 2024-01-22T15:19:33
使用范围: WB ICC IHC
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073
- 传真 :
- 邮箱 : 3193328036@qq.com
Anti-RAD23B Monoclonal Antibody
品牌:solarbio | 货号:K000127M
宿主 | Mouse |
---|---|
英文名称 | Anti-RAD23B Monoclonal Antibody |
别名 | HHR23B;HR23B;P58 |
应用 | WB ICC IHC |
稀释比例 | WB 1:1000. |
蛋白分子量 | 43kDa |
Gene ID | 5887 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG2b |
免疫原 | Purified recombinant human RAD23B protein fragments expressed in E.coli. |
性状 | 液体 |
Subcellular Locations | Cytoplasm Nucleus |
Swiss Prot | P54727 |
克隆号 | 5H1-A10-A7 |
克隆类型 | Monoclonal Antibody |
背景资料 | The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011] |