Anti-PTPN6 单克隆抗体
产品名称: Anti-PTPN6 单克隆抗体
英文名称: Anti-PTPN6 Monoclonal Antibody
产品编号: K000172M
产品价格: null
产品产地: 北京市通州区马驹桥
品牌商标: Solarbio
更新时间: 2023-08-11T10:26:26
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073
- 传真 :
- 邮箱 : 3193328036@qq.com
Anti-PTPN6 Monoclonal Antibody
品牌:solarbio | 货号:K000172M
宿主 | Mouse |
---|---|
英文名称 | Anti-PTPN6 Monoclonal Antibody |
别名 | HCP;HCPH;HPTP1C;PTP-1C;SH-PTP1;SHP-1;SHP-1L;SHP1 |
应用 | WB IP |
稀释比例 | WB 1:1000. |
交叉反应 | Human |
蛋白分子量 | 68kDa |
Gene ID | 5777 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG2a |
免疫原 | Purified recombinant human PTPN6 protein fragments expressed in E.coli. |
性状 | 液体 |
Subcellular Locations | Cytoplasm Nucleus |
Swiss Prot | P29350 |
克隆号 | 2B7-H7-F8 |
克隆类型 | Monoclonal Antibody |
背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. |