Anti-S100B Monoclonal Antibody

品牌：solarbio | 货号：K000176M

英文名称	Anti-S100B Monoclonal Antibody
宿主	Mouse
别名	NEF;S100;S100-B;S100beta
应用	WB
稀释比例	WB 1:500.
交叉反应	Rat
蛋白分子量	11kDa
Gene ID	6285
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	lgG2b
免疫原	Human S100B synthetic peptide conjugated to KLH.
性状	液体
Public Immunogen Range	Human S100B synthetic peptide conjugated to KLH.
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P04271
克隆号	5G3-C11
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008].