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SpringBio高通量抗体芯片上海康成生物工程有限公司

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产品名称: SpringBio高通量抗体芯片
产品型号: SpringBio
产品规格: 1
产品产地: 美国
品牌商标: SpringBio
价    格: 询价
更新时间: 2020/8/20 12:07:42
浏览人数:5304
诚信指数:972点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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产品详细描述

          SpringBio高通量抗体芯片/技术服务


     随着人类基因组计划的完成,在药物研发和疾病治疗中蛋白质组的作用便显得越发重要。芯片技术与传统的低通量蛋白分析方法相比,可以同时检测成百个目标蛋白,在很短的时间内产生大量的数据,因此抗体芯片已成为研究高通量蛋白表达谱的一种有效手段。目前,抗体芯片已经被成功的应用于检测各种癌症以及其他疾病中关键蛋白的相对表达量。
 

较传统的低通量蛋白分析方法之优势

节省时间,一次检测多种蛋白

* 节约样品,减少珍贵样品使用量

* 减少多次实验间的差异对实验结果造成的影响

Springbio
高通量抗体芯片的特点
高密度,一次可检测720个蛋白分子,涉及多种生物学功能
* 特异性高,芯片中的每一种抗体均为WB、IP和IHC级别
* 芯片内探针为两次重复,结果更为准确
图示: Springbio抗体芯片基于抗体抗原特异性结合的原理,
芯片上的抗体能够与样品中的蛋白结合,最终通过荧光信号反应样品中蛋白含量。
 
Springbio高通量抗体芯片(检测722个蛋白)
芯片检测的蛋白涉及多种重要生物学功能
 
Cancer Markers(肿瘤标志物)
Epithelial Membrane Antigen (EMA / CA15-3 / MUC-1), Epithelial Specific Antigen / Ep-CAM, Fli-1, GCDFP-15 (Gross Cystic Disease Fluid Protein-15), Glicentin, Granulocyte (Myeloid cell Marker), Hepatocyte, IPO-38 (Proliferation Marker), Ki-67, L1 Cell Adhesion Molecule, LRP / MVP (Major Vault Protein), MAGE-1, MART-1 / Melan-A (Melanoma Marker), Milk Fat Globule Membrane protein, Human (HMFG1), Muc-1, Mucin 2 (MUC2), Mucin 3 (MUC3), Mucin 5AC (MUC5AC) / Gastric Mucin, Nucleophosmin (NPM), p170 / p-Glycoprotein / MDR (Anti-Hamster), p170 / p-Glycoprotein / MDR, Placental Alk. Phosphatase (PLAP), Progesterone Receptor (Serine190 Phospho-specific), Progesterone Receptor (Serine294 Phospho-specific), Progesterone Receptor, Prostate Specific Acid Phosphatase (PSAP), Prostate Specific Antigen (PSA), pS2 / pNR-2 Estrogen-Regulated Protein, PSCA (Prostate Stem Cell Antigen), PTEN / MMAC1, Renal Cell Carcinoma Marker (gp200), S100 Protein, S100A4, Surfactant Protein A (SP-A), Surfactant Protein B (Mature), Surfactant Protein B (Precursor), Synaptophysin, TAG-72 / CA 72-4, Tartrate Resistant Acid Phosphatase (TRAP), Thomsen-Friedenreich Antigen, Thyroglobulin, Topoisomerase II alpha, Topoisomerase II beta, TTF-1 (Thyroid Transcription Factor-1), Tyrosinase, Tyrosinase Related Protein 75 (TRP75 / gp75)
 
Cell Cycle, Stress Response and DNA Damage Repair(细胞周期、应激反应和DNA损伤修复)
Cell Cycle: APC11(Anaphase-Promoting Complex), APC2 (Anaphase-Promoting Complex), CDC14A Phosphatase, CDC25A, CDC25B, CDC25C, CDC34, CDC37, CDC47 / MCM7, CDC6, CDC7 phosphatase, Cdh1, cdk1 / p34cdc2, Cdk2, Cdk3, Cdk4, Cdk5, Cdk6, cdk7 / p40MO15 / CAK, Cdk8, Chk1, Chk2, Cullin-1 (CUL-1), Cullin-2 (CUL-2), Cullin-3 (CUL-3), Cyclin A, Cyclin B1, Cyclin C, Cyclin D1 / Bcl-1, Cyclin D2, Cyclin D3, Cyclin E, Cyclin E2, Ki-67, Mitochondria, p107, p130 / Rb2, p130Cas, p14ARF / p16Beta, p15INK4b, p16INK4a, p18INK4c, p19ARF, p19INK4d, p19Skp1, p21WAF1, p27Kip1, p35nck5a, p53, p57Kip2, p73, p73alpha , p73alpha/Beta, PCNA (Proliferating Cell Nuclear Antigen), ROC.
 
DNA Damage Repair: DNA Ligase I, DNA Polymerase beta, DNA Polymerase gamma (C-Terminal) (CD7), DNA Primase (p49), DNA Primase (p58), DNA-PKcs, ERCC1, Exo1, Histone H1, Ku (p70 / p80), Ku (p70), Ku (p80), MCM2, MCM5, MDM2, MLH1, RAD1, Rad51, Ribonucleoprotein (RNP), RPA / p32 (Replication Protein A), RPA / p70 (Replication Protein A), RuvA, RuvB, RuvC, sm (Smith Antigen), TdT (Terminal Deoxyribonucleotidyl Transferase), Thymidylate Synthase, Thymine Glycols, Topoisomerase II alpha, Topoisomerase II beta, Xanthine Oxidase / Aldehyde Oxidase, XPA, XPF, XPG / ERCC5, XRCC1 (X-Ray Repair Cross Complementing Protein1), XRCC2 (X-Ray Repair Cross Complementing Protein2).
 
Stress Response: HDJ-2 / DNAJ, Heat Shock Factor 1 (HSF1), Heat Shock Factor 2 (HSF2), Heat Shock Protein 27 (HSP27), Heat Shock Protein 60 (hsp60), Heat Shock Protein 70 (HSP70), Heat Shock Protein 75 / hsp75 / TRAP-1, Heat Shock Protein 90alpha / hsp90alpha (also known as hsp86), Heat Shock Protein 90Beta / hsp90Beta (also known as hsp84), HIF-1alpha (Hypoxia-Inducible Factor-1alpha), HIF-1beta (Hypoxia-Inducible Factor-1beta), Superoxide Dismutase (Cu/Zn).
 
Apoptosis(凋亡)
Cell Senescence: Acinus, AIF (Apoptosis Inducing Factor), ARC (Apoptosis Repressor with CARD), Ask1 / MAPKKK5, BAG-1/RAP46/HAP1, Bak, Bax, Bcl10 / CIPER / CLAP / mE10, Bcl-2alpha, Bcl-6, Bcl-X, Bcl-XL, Bim / BOD (Bcl-2-related Ovarian Death Gene), Caspase 1 / Interleukin-1Beta Converting Enzyme (ICE), Caspase 2, Caspase 3 (CPP32), Caspase 5, Caspase 6 (Mch 2), Caspase 7 (Mch 3), Caspase 8 (FLICE), Caspase 9 / LAP6, Cathepsin D, CD137 (4-1BB), CD14, CD27, CD40, CD95 (Fas), CIDE-A, CIDE-B, D4-GDI, Daxx, DcR1, DcR2 / TRAIL-R4 / TRUNDD, DFF40 (DNA Fragmentation Factor 40) / CAD, DFF45 (DNA Fragmentation Factor 45) / ICAD (Anti-Mouse), DR3 / Apo3 / WSL-1 / TRAMP / LARD, DR5, FADD (FAS-Associated Death Domain-containing Protein), Fas Ligand, FLIP, Granzyme B, I-FLICE / CASPER (Inhibitor of FLICE), MAP-kinase-Activating Death Domain protein / MADD, Mcl-1, PARP (Poly ADP-Ribose Polymerase), PARP (Poly ADP-Ribose Polymerase), Prohibitin (Mitochondrial Marker), RAIDD, SODD (Silencer of Death Domain), Survivin, TR2 / HVEM, TRADD (TNF-R1-Associated Death Domain).
 
Tumor Metastasis(肿瘤转移)
Adhesion Molecule: Cadherin Pan, Cadherin-E / E-Cadherin, Cadherin-P / P-cadherin, CD100 / Leukocyte Semaphorin, CD106 / VCAM, CD138, CD155 / PVR (Poliovirus Receptor), CD165 (gp37), CD18 (Integrin Beta-2), CD26 / DPP IV / ADA-Binding Protein, CD29 (Integrin Beta-1), CD31 / PECAM-1, CD38, CD48, CD50 / ICAM-3, CD54 / ICAM-1, CD56 / NCAM-1, CD57 (Natural Killer Cell Marker), CD6, CD62E / ELAM, CD81 / TAPA-1.
 
Angiogeniss: CD105 / Endoglin / TGF-beta1/3 Receptor, CD31 / PECAM-1, CD34 TypeⅡ(Endothelial Cell Marker), Endostatin, Flk-1 / KDR / VEGFR2, Flt-1 / VEGFR1, Flt-4, Heparan Sulfate Proteoglycan / Perlecan, Thrombospondin (TSP), Thymidine Phosphorylase / PD-ECGF, Vascular Endothelial Growth Factor (VEGF).
 
Cadherin,Catenins and Claudin: Cadherin Pan, Cadherin-E / E-Cadherin, Cadherin-P / P-cadherin, Catenin-beta, Catenin-gamma, Catenin-alpha, Claudin 2, Claudin 3, Claudin 4, Claudin 5, Claudin-1, Connexin 43.
 
Cell Junctions: Cadherin Pan, Cadherin-E / E-Cadherin, Cadherin-P / P-cadherin, Catenin-beta, Catenin-gamma, Catenin-alpha, Claudin 2, Claudin 3, Claudin 4, Claudin 5, Claudin-1, Connexin 43.
 
Cytoskeletal Proteins: Actin Beta, Clathrin , Light Chain, Ezrin / p81 / 80K / Cytovillin, Fascin, Filaggrin, Filamin, Gαi1 G-Protein, Involucrin, Keratin 10 / 13, Keratin 10, Keratin 14, Keratin 15, Keratin 16, Keratin 18 (Phospho-specific Ser33), Keratin 18, Keratin 19, Keratin 20, Keratin 5 / 6 / 18, Keratin 5 / 8, Keratin 6, Keratin 8 (phospho-specific Ser431), Keratin 8 (phospho-specific Ser73), Keratin 8 / 18, Keratin 8, Keratin High Molecular Weight, Keratin Low Molecular Weight, Keratin Multi, Keratin Pan, Moesin, Neurofilament (140-160kDa), Neurofilament (200kDa), Neurofilament (68kDa), Paxillin, L-Plastin, Tubulin-alpha, Tubulin-Beta, Vimentin, Vinculin.
 
Extracellular Matrix Proteins: Collagen II, Collagen IV, Collagen IX, Collagen VII, Endothelial Marker (Small Blood Vessels), Fibrillin-1, Fibronectin, Laminin B1 / Beta1, Laminin B2 / gamma1, Laminin Receptor, Laminin-s, Osteopontin, Tenascin.
 
Proteases & Inhibitors: MMP-1 (Collagenase-1), MMP-10 (Stromelysin-2), MMP-11 (Stromelysin-3), MMP-13 (Collagenase-3), MMP-14 / MT1-MMP, MMP-15 / MT2-MMP, MMP-2 (72kDa Collagenase IV), MMP-23, MMP-3 (Stromelysin-1), MMP-7 (Matrilysin), MMP-9 (92kDa Collagenase IV), PR3 (Proteinase 3), TACE (TNF-alpha converting enzyme) / ADAM17, TIMP-1, TIMP-2. Proteolysis: Cullin-1 (CUL-1), Cullin-2 (CUL-2), Cullin-3 (CUL-3), Ubiquitin.
 
Oncegene(致癌基因)
EGFR family and Receptor Tyrosine Kinase: Amphiregulin, CD115 / c-fms / CSF-1R / M-CSFR, CD117 / c-Kit / SCF-Receptor, c-erbB-2 / HER-2 / neu(21N), c-erbB-3 / HER-3, c-erbB-4 / HER-4, Epidermal Growth Factor Receptor (EGFR), Heregulin / NDF / GGF / Neuregulin.
 
*** homeostasis: Amylin Peptide, Glucose-Regulated Protein 94 (Grp94) / gp96, GLUT-1, GLUT-3, ***, *** Receptor (alpha-Subunit), *** Receptor Substrate-1 (IRS-1), Int-2 Oncoprotein.
 
Transcriptional Regulators: AP-2 Transcription Factor, CBP (CREB-Binding Protein), c-fos, CITED1 (CBP/p300-interacting transactivator 1) / Melanocyte-specific protein 1, c-jun, c-myb / v-myb, c-myc, CREB, DP-1 Transcription Factor, DP-2 Transcription Factor, E2F-1 Transcription Factor, E2F-2 Transcription Factor, E2F-3 Transcription Factor, E2F-4 Transcription Factor, E2F-5 Transcription Factor, Fli-1, Fra2, FRA2 (Fos Related Antigen2), GRIP1 (Glucocorticoid Receptor Interacting Protein 1), HDAC1, Hepatic Nuclear Factor-3Beta (HNF-3Beta), Hepatocyte Factor homologue 4 (HFH-4), HIF-1alpha (Hypoxia-Inducible Factor-1alpha), HIF-1beta (Hypoxia-Inducible Factor-1beta), Microphthalmia (Transcription Factor) (MiTF) , NF kappa B / p50, NF kappa B / p65 (Rel A), 1-Oct, 2-Oct, p300 / CBP, SREBP-1 (Sterol Regulatory Element Binding Protein-1), Stat1, Stat3, Stat5, Stat5a, Stat5b, Stat6 (IL-4 Stat), TTF-1 (Thyroid Transcription Factor-1), Vitamin D Receptor (VDR).
 
Tumor suppressors(抑癌基因)
APC (Adenomateous Polyposis Coli), BRCA2, CD84, FHIT (Fragile Histidine Triad)., MGMT (O-methylguanine-DNA methyltransferase), nm23 / NDP Kinase, p107, p130 / Rb2, p130Cas, p14ARF / p16Beta, p15INK4b, p16INK4a, p21WAF1, p27Kip1, p53, Retinoblastoma (Rb) (Phospho-specific Serine), Retinoblastoma (Rb), SMAD4 / DPC4, von Hippel-Lindau (vHL) Protein, Wilm Tumor Protein (WT1).
 
Cell Differentiation(细胞分化)
Hematopoiesis Diferentiation: CD1a, CD1b, CD32 / Fcgamma Receptor II, CD35 / CR1 (Follicular Dendritic Cell Marker), CD36 / GPIIIb / GPIV, CD41, CD42b (GPIb), CD45RB, CD46, CD47, CD5, CD59 / MACIF / MIRL / Protectin, CD61 / Platelet Glycoprotein IIIA, CD63, CD68 (Macrophage Marker), CD79b (BCR-Ig beta), CD9 (Motility-Related Protein-1), CD94, CD98 / FRP1, CDw78, Factor VIII Related Antigen / von Willebrand Factor, Factor XIII A, Granulocyte (Myeloid cell Marker), Kappa Light Chain, Lambda Light Chain, Lewis A (Blood Group Antigen), Macrophage / L1 Protein / Calprotectin, MHC I (HLA-A), MHC I (HLA-A, B, C), MHC I (HLA-A25 and HLA-Aw32), MHC I (HLA-B), MHC II (HLA-DP), MHC II (HLA-DQ), MHC II (HLA-DR and DP), MHC II (HLA-DR), MHC II (HLA-DR)1α, Microglobulin Beta2, Myeloid Specific marker, p95vav, Pax-5, Plasma Cell marker, Plasminogen.
 
Stem Cell Diferentiation: Activin Receptor Type II (actRII), Alkaline Phosphatase (AP), Alpha Fetoprotein, CD117 / c-Kit / SCF-Receptor, CD29 (Integrin Beta-1), CD30 (Reed-Sternberg Cell Marker), CD34 TypeⅡ(Endothelial Cell Marker), CD38, CD4, CD44 Std. / HCAM, CD45 / T200 / LCA, CD56 / NCAM-1, CD8, CD90 / Thy-1, Collagen II, Collagen IV, Flk-1 / KDR / VEGFR2, GFAP (Glial Fibrillary Acidic Protein), GFAP (Glial Fibrillary Acidic Protein), Glucagon, Heparan Sulfate Proteoglycan / Perlecan, ***, Keratin 10 / 13, Keratin 10, Keratin 14, Keratin 15, Keratin 16, Keratin 18 (Phospho-specific Ser33), Keratin 18, Keratin 19, Keratin 20, Keratin 5 / 6 / 18, Keratin 5 / 8, Keratin 6, Keratin 8 (phospho-specific Ser431), Keratin 8 (phospho-specific Ser73), Keratin 8 / 18, Keratin 8, Keratin High Molecular Weight, Keratin Low Molecular Weight, Keratin Multi, Keratin Pan, MAP 2a,b (Microtubule-Associated Protein), MAP 2a,b,c (Microtubule-Associated Protein), MyoD1, Myosin Smooth Muscle Heavy Chain, 3-Oct, Synaptophysin, tau, Transforming Growth Factor alpha (TGFalpha), Vimentin.
 
 T-cell Markers Diferentiation: B7-H2 (ICOS ligand), CD1, CD100 / Leukocyte Semaphorin, CD137 (4-1BB), CD2 (LFA-2), CD231 (TALLA), CD25 / IL-2Ralpha, CD27, CD3 (Early T Cell Marker), CD3zeta / T Cell Receptor zeta, CD4, CD43 (T-Cell Marker), CD7, CD8, CD84, CDw60 (9-O-acetyl GD3), Perforin.
 
Tumor Signal Transduction(肿瘤信号转导)
G Proteins & G-protein coupled receptors: ADP-ribosylation Factor (ARF) 6, Bonzo / STRL33 / TYMSTR, CXCR4 / Fusin / LESTR / HUMSTR, Gα0 G-Protein, GnRH Receptor / LH-RH Receptor. Hormones: ADP-ribosylation Factor (ARF) 6, Bonzo / STRL33 / TYMSTR, CXCR4 / Fusin / LESTR / HUMSTR, Gα0 G-Protein, GnRH Receptor / LH-RH Receptor, Adrenocorticotrophic Hormone (ACTH), Androgen Receptor, Calcitonin, Cholecystokinin (26-33) (CCK-8), Chorionic Gonadotropin beta, Human (HCG), Estradiol, Estriol, Estrogen Receptor, Follicle Stimulating Hormone (FSH), Follicle Stimulating Hormone-Beta (FSH-Beta), Gastrin 1, Glucagon, Human Growth Hormone (hGH), Inhibin alpha, ***, Leukotriene C4 / D4 / E4, Medroxyprogesterone Acetate (MPA), Parathyroid Hormone Receptor (PTH-Receptor) Type 1, Parathyroid Hormone(PTH), Placental Lactogen (hPL), PPAR gamma, Progesterone, Prolactin, Prolactin Receptor, Retinoic Acid Receptor, Beta (hRARBeta), Retinoid X Receptor, gamma Glutamyl Transferase(gGT), Retinol Binding Protein (RBP), Somatostatin Receptor-1, Testosterone, Thyroid Stimulating Hormone (TSH).
 
Ion Channels: Cystic Fibrosis Transmembrane Regulator (CFTR), GABA α Receptor 1, Human Plasma Membrane Ca2+ Pump (hPMCA), Human Sodium Iodide Symporter (hNIS).
 
Neuroscience: Amyloid A Component, Amyloid A4 , Amyloid Beta, Amyloid A4 Protein Precursor (APP), Apolipoprotein D, Axonal Growth Cones, Calmodulin, CD13 / Aminopeptidase-N, CD56 / NCAM-1, CD90 / Thy-1, Cholecystokinin (26-33) (CCK-8), Chromogranin A, CNPase (Oligodendrocyte & Schwann Cell Marker), CREB, Fascin, GABAA Receptor alpha1, GAD65 (Glutamate Decarboxylase 65), Gastrin 1, GFAP (Glial Fibrillary Acidic Protein), GFAP (Glial Fibrillary Acidic Protein), GluR1, GluR2/3, GluR4, Glycogen Synthase Kinase 3Beta (GSK3Beta), GSK-3, IGF-1 R (alpha-Subunit), IGF-I, IGF-I, MAP 2a,b (Microtubule-Associated Protein), MAP 2a,b,c (Microtubule-Associated Protein), mGluR1 / Grm1 / Metabotropic glutamate receptor 1, mGluR5, Myelin / Oligodendrocyte, Neurofilament (140-160kDa), Neurofilament (200kDa), Neurofilament (68kDa), Neuron Specific Enolase / NSE, Neurotrophin Receptor /NGF-Receptor (p75NGFR), Nitric Oxide Synthase, brain (bNOS), Nitric Oxide Synthase, endothelial (eNOS), Nitric Oxide Synthase, inducible (iNOS), Nitric Oxide Synthase, universal (u-NOS), Notch, p35nck5a, Pan Synuclein, Parkin, PCTAIRE2, PMP-22 (Peripheral Myelin Protein), Presenilin 1 (PS-1), Prostate Apoptosis Response-4, Protein Gene Product 9.5, Ret Oncoprotein, S100 Protein, S100A4, Synaptophysin, Synuclein, Synuclein Beta, tau, Transglutaminase II, Urocortin.
 
Other(其他)
6-Histidine (Epitope Tagging), Beta-Galactosidase, Biotin, Bromodeoxyuridine (BrdU), Bromodeoxyuridine (BrdU), Fluorescein Isothiocyanate (FITC), GFP (Green Fluorescent Protein), GST (Epitope Tagging), HA (Hemagglutinin), Luciferase, Maltose Binding Protein.
 
 
SpringBio高通量抗体芯片技术服务详细介绍请访问:http://www.kangchen.com.cn/service/Servicemain.asp?id=83
 
 
 

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生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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