PeproTech重组人TGF-beta2-Mammalian 1000ug-细胞/细菌培养-试剂-生物在线
PeproTech重组人TGF-beta2-Mammalian 1000ug

PeproTech重组人TGF-beta2-Mammalian 1000ug

商家询价

产品名称: PeproTech重组人TGF-beta2-Mammalian 1000ug

英文名称: Recombinant Human TGF-beta2-Mammalian

产品编号: 100-35B

产品价格: 0

产品产地: 美国

品牌商标: PeproTech

更新时间: null

使用范围: null

美国PeproTech(派普泰克)公司中国代表处
  • 联系人 :
  • 地址 :  江苏省苏州市工业园区星湖街218号A1北座4楼L03
  • 邮编 : 215123
  • 所在区域 : 江苏
  • 电话 :
  • 传真 : 0512-68325993
  • 邮箱 : peprotech.infochina@thermofisher.com

 

Human Growth Factors & Cytokines

Recombinant Human TGF-β2 (mammalian derived)



 
 

Synonyms :

Transforming Growth Factor-beta2, Glioblastoma-derived T cell suppressor factor, BSC-1, Cetermin, Polyergin

Description :

The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Catalog #:

100-35B

Source :

A293 cells

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED50 was found to be ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW KWIHEPKGYN ANFCAGACPY LWSSDTQHSR VLSLYNTINP EASASPCCVS QDLEPLTILY YIGKTPKIEQ LSNMIVKSCK CS

PubMed Link :

TGF+AND+beta+AND+2

Country of Origin :

USA

 

 

Size A 1μg $80   
 
Size B 5μg $195   
 
Size C 1mg $9800   
 

 


 

Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.

 

Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.